Full Product Name
IKZF4 Antibody
Product Gene Name
anti-IKZF4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H2S9
Species Reactivity
Human, Mouse, Rat
Specificity
IKZF4 Antibody detects endogenous levels of IKZF4.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human IKZF4.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-IKZF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IKZF4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-IKZF4 antibody
WB: 1:500~1:1000
ELISA: 1:10000
Western Blot (WB) of anti-IKZF4 antibody
Western blot analysis of the lysates from HeLa cells using IKZF4 antibody.
NCBI/Uniprot data below describe general gene information for IKZF4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071910.3
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NCBI GenBank Nucleotide #
NM_022465.3
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UniProt Primary Accession #
Q9H2S9
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UniProt Secondary Accession #
Q96JP3[Other Products]
UniProt Related Accession #
Q9H2S9[Other Products]
NCBI Official Full Name
zinc finger protein Eos isoform a
NCBI Official Synonym Full Names
IKAROS family zinc finger 4
NCBI Official Symbol
IKZF4 [Similar Products]
NCBI Official Synonym Symbols
EOS; ZNFN1A4
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NCBI Protein Information
zinc finger protein Eos
UniProt Protein Name
Zinc finger protein Eos
UniProt Synonym Protein Names
Ikaros family zinc finger protein 4
Protein Family
Zinc finger protein
UniProt Gene Name
IKZF4 [Similar Products]
UniProt Synonym Gene Names
KIAA1782; ZNFN1A4 [Similar Products]
NCBI Summary for IKZF4
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
UniProt Comments for IKZF4
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 ().
Research Articles on IKZF4
1. IKZF4 polymorphism (rs1701704) was strongly associated with insulin autobody positivity at the time of type 1 diabetes diagnosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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