Full Product Name
JAG1 Polyclonal Antibody
Product Synonym Names
AGS; AHD; AWS; CD 339; CD339; CD339 antigen; Headturner; hJ1; Htu; Jag 1; Jag1; JAG1; Jagged 1; Jagged1 (Alagille syndrome); Jagged1; JAGL1; MGC104644; OTTHUMP00000030278; Protein jagged-1; Ser 1; Ser1; Serrate 1; Slalom
Product Gene Name
anti-JAG1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9QXX0
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
140 mug/mL (lot specific)
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse Jagged1
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-JAG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-JAG1 antibody
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Product Categories/Family for anti-JAG1 antibody
Cancer; Cardiovascular; Neuroscience; Stem Cells
Applications Tested/Suitable for anti-JAG1 antibody
Immunohistochemistry (IHC)
Application Notes for anti-JAG1 antibody
IHC: 1:200-1:400
Immunohistochemistry (IHC) of anti-JAG1 antibody
Immunohistochemistry analysis of paraffin-embedded rat testis using JAG1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry (IHC) of anti-JAG1 antibody
Immunohistochemistry analysis of paraffin-embedded rat uterus using JAG1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry (IHC) of anti-JAG1 antibody
Immunohistochemistry analysis of paraffin-embedded rat brain using JAG1 Polyclonal Antibody at dilution of 1:200.
NCBI/Uniprot data below describe general gene information for JAG1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_038850.1
[Other Products]
NCBI GenBank Nucleotide #
NM_013822.5
[Other Products]
UniProt Primary Accession #
Q9QXX0
[Other Products]
UniProt Secondary Accession #
Q63722[Other Products]
UniProt Related Accession #
Q9QXX0[Other Products]
Molecular Weight
134,164 Da
NCBI Official Full Name
protein jagged-1
NCBI Official Synonym Full Names
jagged 1
NCBI Official Symbol
Jag1 [Similar Products]
NCBI Official Synonym Symbols
Htu; Ozz; ABE2; Ser-1; Gsfabe2
[Similar Products]
NCBI Protein Information
protein jagged-1
UniProt Protein Name
Protein jagged-1
UniProt Synonym Protein Names
CD_antigen: CD339
Protein Family
Protein jagged
UniProt Gene Name
Jag1 [Similar Products]
UniProt Synonym Gene Names
Jagged1 [Similar Products]
UniProt Comments for JAG1
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (). May regulate fibroblast growth factor-induced angiogenesis.
Research Articles on JAG1
1. Our findings reveal deep conservation of Jagged1-Notch2 signaling in patterning the pharyngeal arches from fish to mouse to man, despite the very different functions of their skeletal derivatives in jaw support and sound transduction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
