Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK), Polyclonal Antibody

Muscle-specific tyrosine-protein kinase receptor; Muscle-specific kinase receptor

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

200ug/ml (lot specific)

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of anti-MUSK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

96,822 Da

muscle associated receptor tyrosine kinase

muscle, skeletal receptor tyrosine protein kinase

Muscle, skeletal receptor tyrosine protein kinase

MuSK; Muscle-specific kinase receptor  [Similar Products]

receptor tyrosine kinase expressed in myotomes, developing muscle and localized to the neuromuscular junction in the *****; expression is induced in response to injury or immobilization [RGD, Feb 2006]

MUSK: a receptor tyrosine kinase that is essential for the establishment and maintenance of the neuromuscular junction (NMJ). Its activation by agrin, a neuronally derived heparan-sulfate proteoglycan, and the agrin receptor (LRP4), leads to clustering of acetylcholine receptors on the postsynaptic side of the NMJ. Its activation by agrin requires Dok7, which interacts with the cytoplasmic portion of MuSK and activates its tyrosine kinase activity.

Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Musk family; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group

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