Product Name
Myotubularin-related protein 13 (SBF2), Recombinant Protein
Full Product Name
Recombinant Human Myotubularin-related protein 13 (SBF2) , partial
Product Gene Name
SBF2 recombinant protein
[Similar Products]
Product Synonym Gene Name
SBF2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q86WG5
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SBF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SBF2 recombinant protein
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2.
NCBI/Uniprot data below describe general gene information for SBF2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112224.1
[Other Products]
NCBI GenBank Nucleotide #
NM_030962.3
[Other Products]
UniProt Primary Accession #
Q86WG5
[Other Products]
UniProt Secondary Accession #
Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q96FE2; Q9C097[Other Products]
UniProt Related Accession #
Q86WG5[Other Products]
Molecular Weight
129,344 Da
NCBI Official Full Name
myotubularin-related protein 13
NCBI Official Synonym Full Names
SET binding factor 2
NCBI Official Symbol
SBF2 [Similar Products]
NCBI Official Synonym Symbols
CMT4B2; MTMR13; DENND7B
[Similar Products]
NCBI Protein Information
myotubularin-related protein 13
UniProt Protein Name
Myotubularin-related protein 13
UniProt Synonym Protein Names
SET-binding factor 2
Protein Family
Myotubularin-related protein
UniProt Gene Name
SBF2 [Similar Products]
UniProt Synonym Gene Names
CMT4B2; KIAA1766; MTMR13 [Similar Products]
NCBI Summary for SBF2
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
UniProt Comments for SBF2
Guanine nucleotide exchange factor (GEF) which may activate RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Research Articles on SBF2
1. Rare variants in SBF2 predict an increased risk of taxane-induced peripheral neuropathy in African American breast cancer patients receiving paclitaxel.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.