Product Name
Prealbumin (TTR), Monoclonal Antibody
Full Product Name
Prealbumin
Product Synonym Names
TTR; Transthyretin; ATTR; Prealbumin; TBPA
Product Gene Name
anti-TTR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02766
Purity/Purification
ProA affinity purified
Immunogen
Recombinant Protein
Storage Buffer
1*TBS (pH7.4), 1% BSA, 40% Glycerol.
Preservative
0.05% Sodium Azide.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-TTR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TTR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for TTR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000362.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000371.3
[Other Products]
UniProt Primary Accession #
P02766
[Other Products]
UniProt Secondary Accession #
Q549C7; Q6IB96; Q9UBZ6; Q9UCM9[Other Products]
UniProt Related Accession #
P02766[Other Products]
Molecular Weight
15,887 Da[Similar Products]
NCBI Official Full Name
transthyretin
NCBI Official Synonym Full Names
transthyretin
NCBI Official Symbol
TTR [Similar Products]
NCBI Official Synonym Symbols
CTS; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651
[Similar Products]
NCBI Protein Information
transthyretin
UniProt Protein Name
Transthyretin
UniProt Synonym Protein Names
ATTR; Prealbumin; TBPA
Protein Family
Transthyretin
UniProt Gene Name
TTR [Similar Products]
UniProt Synonym Gene Names
PALB [Similar Products]
NCBI Summary for TTR
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
UniProt Comments for TTR
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Research Articles on TTR
1. G might influence the constitutive splicing of TTR mRNA">could potentially downregulate the TTR promoter activity; c.200+4A>G might influence the constitutive splicing of TTR mRNA
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
