Full Product Name
PIBF1 Antibody - middle region
Product Gene Name
anti-PIBF1 antibody
[Similar Products]
Product Synonym Gene Name
PIBF; CEP90; C13orf24;[Similar Products]
Antibody/Peptide Pairs
PIBF1 peptide (MBS3245337) is used for blocking the activity of PIBF1 antibody (MBS3220535)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: ETYEEDRKNY SEVQIRCQRL ALELADTKQL IQQGDYRQEN YDKVKSERDA
3D Structure
ModBase 3D Structure for Q8WXW3
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 16% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PIBF1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-PIBF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-PIBF1 antibody
Polyclonal; Cell Biology; Immunology;
Applications Tested/Suitable for anti-PIBF1 antibody
Western Blot (WB)
Western Blot (WB) of anti-PIBF1 antibody
Host: Rabbit
Target Name: PIBF1
Sample Tissue: Thyroid Tumor lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for PIBF1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006337.2
[Other Products]
NCBI GenBank Nucleotide #
NM_006346.2
[Other Products]
UniProt Primary Accession #
Q8WXW3
[Other Products]
UniProt Related Accession #
Q8WXW3[Other Products]
NCBI Official Full Name
progesterone-induced-blocking factor 1 isoform 2
NCBI Official Synonym Full Names
progesterone immunomodulatory binding factor 1
NCBI Official Symbol
PIBF1 [Similar Products]
NCBI Official Synonym Symbols
PIBF; CEP90; JBTS33; C13orf24
[Similar Products]
NCBI Protein Information
progesterone-induced-blocking factor 1
UniProt Protein Name
Progesterone-induced-blocking factor 1
Protein Family
Progesterone-induced-blocking factor
UniProt Gene Name
PIBF1 [Similar Products]
UniProt Synonym Gene Names
C13orf24; PIBF [Similar Products]
UniProt Entry Name
PIBF1_HUMAN
NCBI Summary for PIBF1
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]
UniProt Comments for PIBF1
PIBF1: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q22.1
Cellular Component: centrosome
Molecular Function: protein binding
Research Articles on PIBF1
1. We found at high levels of expression of PIBF protein in epithelial ovarian cancer patients. These data demonstrate that tumor cells can secrete PIBF to escape the immune system
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
