Full Product Name
PIBF1 Antibody
Product Synonym Names
PIBF; CEP90; C13orf24; RP11-505F3.1
Product Gene Name
anti-PIBF1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8WXW3
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
A synthetic peptide of human PIBF1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-PIBF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PIBF1 antibody
Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has also been named CEP90. Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
Product Categories/Family for anti-PIBF1 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-PIBF1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PIBF1 antibody
WB: 1:500-1:1000
IHC: 1:50-1:100
Western Blot (WB) of anti-PIBF1 antibody
Western blot analysis of extracts of various celllines, using PIBF1antibody.
Testing Data of anti-PIBF1 antibody
Immunohistochemistry (IHC) of anti-PIBF1 antibody
Immunohistochemistryof paraffin-embeddedhuman colon tissue usingPIBF1antibody.
NCBI/Uniprot data below describe general gene information for PIBF1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006337.2
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NCBI GenBank Nucleotide #
NM_006346.3
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UniProt Primary Accession #
Q8WXW3
[Other Products]
UniProt Secondary Accession #
O95664; Q6U9V2; Q6UG50; Q86V07; Q96SF4[Other Products]
UniProt Related Accession #
Q8WXW3[Other Products]
NCBI Official Full Name
progesterone-induced-blocking factor 1 isoform 2
NCBI Official Synonym Full Names
progesterone immunomodulatory binding factor 1
NCBI Official Symbol
PIBF1 [Similar Products]
NCBI Official Synonym Symbols
PIBF; CEP90; JBTS33; C13orf24
[Similar Products]
NCBI Protein Information
progesterone-induced-blocking factor 1
UniProt Protein Name
Progesterone-induced-blocking factor 1
UniProt Synonym Protein Names
Centrosomal protein of 90 kDa; CEP90
Protein Family
Progesterone-induced-blocking factor
UniProt Gene Name
PIBF1 [Similar Products]
UniProt Synonym Gene Names
C13orf24; PIBF; PIBF; CEP90 [Similar Products]
NCBI Summary for PIBF1
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]
UniProt Comments for PIBF1
Isoform 1: Pericentriolar protein required to maintain mitotic spindle pole integrity (PubMed:21224392). Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation (PubMed:23110211). Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 (PubMed:26297806).
Research Articles on PIBF1
1. blood and placental tissue level expression of PIBF is concordant and correlates with both progesterone receptor expression status as well as final pregnancy outcome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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