Full Product Name
Anti-Mouse CD41 Monoclonal Antibody (PE Conjugated) [MWReg30]
Product Synonym Names
Itga2b; GPalpha Iib; CD41; GPIIb
Product Gene Name
anti-CD41 antibody
[Similar Products]
Product Synonym Gene Name
Mouse CD41[Similar Products]
Matching Pairs
Antibody: CD41 Clone #MWReg30 (MBS2559310)
Isotype Control: IgG1, kappa Clone #HRPN (MBS2557828)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9QUM0
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Concentration
0.5 mg/mL (lot specific)
Preparation and Storage
Store at 2-8 degree C and protect from prolonged exposure to light. Do not freeze.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CD41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD41 antibody
CD41, also known as integrin alpha2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin beta3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.
Applications Tested/Suitable for anti-CD41 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD41 antibody
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 2 ug per 106 cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
NCBI/Uniprot data below describe general gene information for CD41. It may not necessarily be applicable to this product.
NCBI Accession #
NP_034705.2
[Other Products]
NCBI GenBank Nucleotide #
NP_034705.2
[Other Products]
UniProt Primary Accession #
Q9QUM0
[Other Products]
UniProt Related Accession #
Q9QUM0[Other Products]
NCBI Official Full Name
integrin alpha-IIb
NCBI Official Synonym Full Names
integrin alpha 2b
NCBI Official Symbol
Itga2b [Similar Products]
NCBI Official Synonym Symbols
CD41; CD41B; GpIIb; AI172977; alphaIIb
[Similar Products]
NCBI Protein Information
integrin alpha-IIb
UniProt Protein Name
Integrin alpha-IIb
UniProt Synonym Protein Names
GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb
UniProt Gene Name
Itga2b [Similar Products]
UniProt Entry Name
ITA2B_MOUSE
Research Articles on CD41
1. Mimic chronic immune thrombocytopaenia using murine platelet induced model through immunized CD41-knockout mice.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
