Product Name
Coiled-coil alpha-helical rod protein 1 (CCHCR1), Recombinant Protein
Full Product Name
Recombinant Human Coiled-coil alpha-helical rod protein 1 (CCHCR1)
Product Gene Name
CCHCR1 recombinant protein
[Similar Products]
Product Synonym Gene Name
CCHCR1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-782aa, full length protein
Sequence
MFPPSGSTGL IPPSHFQARP LSTLPRMAPT WLSDIPLVQP PGHQDVSERR LDTQRPQVTM WERDVSSDRQ EPGRRGRSWG LEGSQALSQQ AEVIVRQLQE LRRLEEEVRL LRETSLQQKM RLEAQAMELE ALARAEKAGR AEAEGLRAAL AGAEVVRKNL EEGSQRELEE VQRLHQEQLS SLTQAHEEAL SSLTSKAEGL EKSLSSLETR RAGEAKELAE AQREAELLRK QLSKTQEDLE AQVTLVENLR KYVGEQVPSE VHSQTWELER QKLLETMQHL QEDRDSLHAT AELLQVRVQS LTHILALQEE ELTRKVQPSD SLEPEFTRKC QSLLNRWREK VFALMVQLKA QELEHSDSVK QLKGQVASLQ EKVTSQSQEQ AILQRSLQDK AAEVEVERMG AKGLQLELSR AQEARRRWQQ QTASAEEQLR LVVNAVSSSQ IWLETTMAKV EGAAAQLPSL NNRLSYAVRK VHTIRGLIAR KLALAQLRQE SCPLPPPVTD VSLELQQLRE ERNRLDAELQ LSARLIQQEV GRAREQGEAE RQQLSKVAQQ LEQELQQTQE SLASLGLQLE VARQGQQEST EEAASLRQEL TQQQELYGQA LQEKVAEVET RLREQLSDTE RRLNEARREH AKAVVSLRQI QRRAAQEKER SQELRRLQEE ARKEEGQRLA RRLQELERDK NLMLATLQQE GLLSRYKQQR LLTVLPSLLD KKKSVVSSPR PPECSASAPV AAAVPTRESI KGSLSVLLDD LQDLSEAISK EEAVCQGDNL DRCSSSNPQM SS
3D Structure
ModBase 3D Structure for Q8TD31
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CCHCR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CCHCR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001099033.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001105563.1
[Other Products]
UniProt Primary Accession #
Q8TD31
[Other Products]
UniProt Secondary Accession #
Q2TB67; Q5SQ82; Q5STE9; Q9NRK8; Q9NWY9; Q9NXJ4; Q9NXK3; Q9Y6W1; Q9Y6W2; A2ABH6; E9PE84[Other Products]
UniProt Related Accession #
Q8TD31[Other Products]
Molecular Weight
95,145 Da
NCBI Official Full Name
coiled-coil alpha-helical rod protein 1 isoform 2
NCBI Official Synonym Full Names
coiled-coil alpha-helical rod protein 1
NCBI Official Symbol
CCHCR1 [Similar Products]
NCBI Official Synonym Symbols
HCR; SBP; pg8; C6orf18
[Similar Products]
NCBI Protein Information
coiled-coil alpha-helical rod protein 1
UniProt Protein Name
Coiled-coil alpha-helical rod protein 1
UniProt Synonym Protein Names
Alpha-helical coiled-coil rod protein; Putative gene 8 protein; Pg8
Protein Family
Coiled-coil alpha-helical rod protein
UniProt Gene Name
CCHCR1 [Similar Products]
UniProt Synonym Gene Names
C6orf18; HCR; Pg8 [Similar Products]
NCBI Summary for CCHCR1
This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]
UniProt Comments for CCHCR1
May be a regulator of keratinocyte proliferation or differentiation.
Research Articles on CCHCR1
1. CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
