Full Product Name
MCT12 Polyclonal Antibody
Product Gene Name
anti-MCT12 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6ZSM3
Other Notes
Small volumes of anti-MCT12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MCT12. It may not necessarily be applicable to this product.
NCBI Accession #
NP_998771.3
[Other Products]
NCBI GenBank Nucleotide #
NM_213606.3
[Other Products]
UniProt Primary Accession #
Q6ZSM3
[Other Products]
UniProt Secondary Accession #
Q5M9M9; Q5T7J2; Q6ZV76[Other Products]
UniProt Related Accession #
Q6ZSM3[Other Products]
Molecular Weight
53,075 Da
NCBI Official Full Name
monocarboxylate transporter 12
NCBI Official Synonym Full Names
solute carrier family 16 member 12
NCBI Official Symbol
SLC16A12 [Similar Products]
NCBI Official Synonym Symbols
CJMG; CRT2; MCT12; CTRCT47
[Similar Products]
NCBI Protein Information
monocarboxylate transporter 12
UniProt Protein Name
Monocarboxylate transporter 12
UniProt Synonym Protein Names
Creatine transporter 2
UniProt Gene Name
SLC16A12 [Similar Products]
UniProt Synonym Gene Names
MCT12; CRT2 [Similar Products]
NCBI Summary for MCT12
This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010]
UniProt Comments for MCT12
Proton-linked monocarboxylate transporter that mediates creatine transport across the plasma membrane.
Research Articles on MCT12
1. We screened the coding exons of the gene SLC16A12 in 877 patients. Their impact on creatine transport was tested in Xenopus laevis oocytes and human HEK293T cells. Four variants (p.Ser158Pro, p.Gly205Val, p.Pro395Gln and p.Ser453Arg) displayed severe reduction in both model systems. Our findings provide insight into molecular requirements of creatine transporter.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
