Product Name
SLC16A12, Polyclonal Antibody
Full Product Name
SLC16A12 Polyclonal Antibody
Product Synonym Names
CJMG; MCT12
Product Gene Name
anti-SLC16A12 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.5mg/mL (lot specific)
Immunogen
Synthetic peptide of human SLC16A12
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-SLC16A12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC16A12 antibody
This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria.
Applications Tested/Suitable for anti-SLC16A12 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-SLC16A12 antibody
IHC: 1:25-1:100
Immunohistochemistry (IHC) of anti-SLC16A12 antibody
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using SLC16A12 Polyclonal Antibody at dilution 1:30
NCBI/Uniprot data below describe general gene information for SLC16A12. It may not necessarily be applicable to this product.
NCBI Accession #
AAH86873.1
[Other Products]
UniProt Secondary Accession #
Q5M9M9; Q5T7J2; Q6ZV76[Other Products]
UniProt Related Accession #
Q6ZSM3[Other Products]
Molecular Weight
53,075 Da
NCBI Official Full Name
SLC16A12 protein, partial
NCBI Official Synonym Full Names
solute carrier family 16, member 12
NCBI Official Symbol
SLC16A12 [Similar Products]
NCBI Official Synonym Symbols
CJMG; CRT2; MCT12
[Similar Products]
NCBI Protein Information
monocarboxylate transporter 12; creatine transporter 2; monocarboxylic acid transporter 12; solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
UniProt Protein Name
Monocarboxylate transporter 12
UniProt Synonym Protein Names
Creatine transporter 2
Protein Family
Monocarboxylate transporter
UniProt Gene Name
SLC16A12 [Similar Products]
UniProt Synonym Gene Names
MCT 12 [Similar Products]
UniProt Entry Name
MOT12_HUMAN
NCBI Summary for SLC16A12
This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010]
UniProt Comments for SLC16A12
SLC16A12: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG). Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q23.31
Cellular Component: integral to plasma membrane
Molecular Function: creatine transporter activity; symporter activity; lactate transmembrane transporter activity
Disease: Cataract, Juvenile, With Microcornea And Glucosuria
Research Articles on SLC16A12
1. study identified a second creatine transporter monocarboxylate transporter 12 (MCT12), encoded by the cataract and glucosuria associated gene SLC16A12; Rssults show SLC6A8 was predominantly found in brain, heart and muscle, while SLC16A12 was more abundant in kidney and retina. In the lens, the two transcripts were found at comparable levels.
Precautions
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Disclaimer
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