Product Name
FIGF, Recombinant Protein
Full Product Name
Recombinant Mouse FIGF Protein
Product Synonym Names
VEGFD; Vascular endothelial growth factor D; VEGF-D; c-Fos-induced growth factor; FIGF
Product Gene Name
FIGF recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
FYDTETLKVI DEEWQRTQCS PRETCVEVAS ELGKTTNTFF KPPCVNVFRC GGCCNEEGVM CMNTSTSYIS KQLFEISVPL TSVPELVPVK IANHTGCKCL PTGPRHPYSV DHHHHHH
3D Structure
ModBase 3D Structure for P97946
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Other Notes
Small volumes of FIGF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FIGF recombinant protein
Recombinant Mouse FIGF Protein is produced by our mammalian expression system and the target gene encoding Phe98-Ser206 is expressed with a 6His tag at the C-terminus.
Applications Tested/Suitable for FIGF recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
NCBI/Uniprot data below describe general gene information for FIGF. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001295418.1
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NCBI GenBank Nucleotide #
NM_001308489.1
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UniProt Primary Accession #
P97946
[Other Products]
UniProt Secondary Accession #
A2AIH3[Other Products]
UniProt Related Accession #
P97946[Other Products]
Molecular Weight
40,909 Da
NCBI Official Full Name
vascular endothelial growth factor D isoform VEGF-D326 preproprotein
NCBI Official Synonym Full Names
vascular endothelial growth factor D
NCBI Official Symbol
Vegfd [Similar Products]
NCBI Official Synonym Symbols
Figf; VEGF-D; AI325264
[Similar Products]
NCBI Protein Information
vascular endothelial growth factor D
UniProt Protein Name
Vascular endothelial growth factor D
UniProt Synonym Protein Names
c-Fos-induced growth factor; FIGF
UniProt Gene Name
Vegfd [Similar Products]
UniProt Synonym Gene Names
VEGF-D; FIGF [Similar Products]
UniProt Entry Name
VEGFD_MOUSE
NCBI Summary for FIGF
This gene encodes a member of the vascular endothelial growth factor (VEGF) family that acts as a ligand for vascular endothelial growth factor receptor 3. Signalling through this protein is important for growth and development of endothelial and vascular tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
UniProt Comments for FIGF
VEGFD: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in *****s. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Belongs to the PDGF/VEGF growth factor family.
Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: extracellular region; extracellular space
Molecular Function: chemoattractant activity; growth factor activity; platelet-derived growth factor receptor binding; protein binding; protein homodimerization activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 3 binding; vascular endothelial growth factor receptor binding
Biological Process: angiogenesis; cell proliferation; induction of positive chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of interleukin-6 production; regulation of vascular endothelial growth factor receptor signaling pathway; response to hypoxia; vascular endothelial growth factor receptor signaling pathway
Research Articles on FIGF
1. These results suggest that lymph node lymphangiogenesis occurs before metastasis in OSCC. VEGF-A and VEGF-D play critical roles in this process.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
