Full Product Name
5-HT-5A Antibody
Product Synonym Names
5-hydroxytryptamine receptor 5A; 5-HT-5A; Serotonin receptor 5A; 5-HT-5
Product Gene Name
anti-5-HT-5A antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P47898
Specificity
5-HT-5A antibody detects endogenous levels of total 5-HT-5A protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human 5-HT-5A.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-5-HT-5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-5-HT-5A antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-5-HT-5A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-5-HT-5A antibody
WB: 1:500~1:1000
ELISA: 1:20000
Western Blot (WB) of anti-5-HT-5A antibody
Western blot analysis of extracts from HeLa cells, using 5-HT-5A antibody.
NCBI/Uniprot data below describe general gene information for 5-HT-5A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_076917.1
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NCBI GenBank Nucleotide #
NM_024012.3
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UniProt Primary Accession #
P47898
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UniProt Secondary Accession #
Q2M2D2[Other Products]
UniProt Related Accession #
P47898[Other Products]
Molecular Weight
40,255 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 5A
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 5A
NCBI Official Symbol
HTR5A [Similar Products]
NCBI Official Synonym Symbols
5-HT5A
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NCBI Protein Information
5-hydroxytryptamine receptor 5A
UniProt Protein Name
5-hydroxytryptamine receptor 5A
UniProt Synonym Protein Names
Serotonin receptor 5A
UniProt Gene Name
HTR5A [Similar Products]
UniProt Synonym Gene Names
5-HT-5; 5-HT-5A; 5-HT5A [Similar Products]
NCBI Summary for 5-HT-5A
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
UniProt Comments for 5-HT-5A
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
Product References and Citations for anti-5-HT-5A antibody
Rees S., FEBS Lett. 355:242-246(1994). The MGC Project Team, Genome Res. 14:2121-2127(2004). Sjoeblom T., nce 314:268-274(2006).
Research Articles on 5-HT-5A
1. Results suggest that TPH1 218A/C and HTR5A 12A/T polymorphisms cannot predict treatment response in major depression
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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