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5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein

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产品名称: 5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein
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简单介绍

5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein


5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein  的详细介绍
Product Name

5-hydroxytryptamine receptor 1D (Htr1d), Recombinant Protein

Full Product Name

Recombinant Rat 5-hydroxytryptamine receptor 1D (Htr1d)

Product Synonym Names
Recombinant 5-hydroxytryptamine receptor 1D (Htr1d); 5-hydroxytryptamine receptor 1D; 5-HT-1D; 5-HT1D; Serotonin receptor 1D
Product Gene Name

Htr1d recombinant protein

[Similar Products]
Product Synonym Gene Name
Htr1d[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
1-374
Sequence
MSLPNQSLEG LPQEASNRSL NATGAWDPEV LQALRISLVV VLSIITLATV LSNAFVLTTI LLTKKLHTPA NYLIGSLATT DLLVSILVMP ISIAYTTTRT WNFGQILCDI WVSSDITCCT ASILHLCVIA LDRYWAITDA LEYSKRRTAG HAAAMIAAVW AISICISIPP LFWRQATAHE EMSDCLVNTS QISYTIYSTC GAFYIPSILL IILYGRIYVA ARSRILNPPS LYGKRFTTAQ LITGSAGSSL CSLNPSLHES HTHTVGSPLF FNQVKIKLAD SILERKRISA ARERKATKTL GIILGAFIIC WLPFFVVSLV LPICRDSCWI HPALFDFFTW LGYLNSLINP VIYTVFNEDF RQAFQRVVHF RKAS
Chromosome Location
Chromosome: 5; NC_005104.3 (158566277..158567401). Location: 5q36
3D Structure
ModBase 3D Structure for P28565
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Htr1d recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Htr1d. It may not necessarily be applicable to this product.
NCBI GI #
6981056
NCBI GeneID
25323
NCBI Accession #
NP_036984.1 [Other Products]
NCBI GenBank Nucleotide #
NM_012852.1 [Other Products]
UniProt Primary Accession #
P28565 [Other Products]
UniProt Related Accession #
P28565[Other Products]
Molecular Weight
41,540 Da[Similar Products]
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NCBI Official Full Name
5-hydroxytryptamine receptor 1D
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
NCBI Official Symbol
Htr1d  [Similar Products]
NCBI Official Synonym Symbols
5HT1D
  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1D; 5-HT1D; 5-HT-1D; serotonin receptor 1D; 5 - Hydroxytryptamine (serotonin) receptor 1D
UniProt Protein Name
5-hydroxytryptamine receptor 1D
UniProt Synonym Protein Names
Serotonin receptor 1D
Protein Family
5-hydroxytryptamine receptor
UniProt Gene Name
Htr1d  [Similar Products]
UniProt Synonym Gene Names
5-HT-1D; 5-HT1D  [Similar Products]
UniProt Entry Name
5HT1D_RAT
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NCBI Summary for Htr1d
G-protein coupled receptor for serotonin; found in nociceptors throughout the body [RGD, Feb 2006]
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UniProt Comments for Htr1d
5-HT(1D): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Cellular Component: integral to plasma membrane

Molecular Function: serotonin binding; serotonin receptor activity

Biological Process: regulation of locomotion; vasoconstriction; synaptic transmission; intestine smooth muscle contraction; response to toxin; G-protein signaling, adenylate cyclase inhibiting pathway; serotonin receptor signaling pathway; regulation of behavior
Research Articles on Htr1d
1. The mRNA and protein expressions of 5-HT1D receptor decreased in excessive fatigue rats and restraint stress rats.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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