Full Product Name
Rabbit GPR126 Antibody
Product Gene Name
anti-GPR126 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 6; NC_000006.11 (142623056..142767403). Location: 6q24.1
3D Structure
ModBase 3D Structure for Q86SQ4
Species Reactivity
Human, mouse
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Other Notes
Small volumes of anti-GPR126 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GPR126 antibody
Immunofluorescence (IF), ELISA (EIA)
NCBI/Uniprot data below describe general gene information for GPR126. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001027566.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001032394.2
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UniProt Primary Accession #
Q86SQ4
[Other Products]
UniProt Secondary Accession #
Q5TGN7; Q6DHZ4; Q6F3F5; Q6F3F6; Q6F3F7; Q6F3F8; Q6MZU7; Q8IXA4; Q8NC14; Q96JW0[Other Products]
UniProt Related Accession #
Q86SQ4[Other Products]
Molecular Weight
136,695 Da
NCBI Official Full Name
G-protein coupled receptor 126 isoform alpha 2
NCBI Official Synonym Full Names
G protein-coupled receptor 126
NCBI Official Symbol
GPR126 [Similar Products]
NCBI Official Synonym Symbols
APG1; DREG; VIGR; PS1TP2
[Similar Products]
NCBI Protein Information
G-protein coupled receptor 126; HBV PreS1-transactivated protein 2; vascular inducible G protein-coupled receptor; vascular-inducible G protein-coupled receptor; developmentally regulated G-protein-coupled receptor
UniProt Protein Name
G-protein coupled receptor 126
UniProt Synonym Protein Names
Developmentally regulated G-protein-coupled receptor; Vascular inducible G protein-coupled receptor
Protein Family
G-protein coupled receptor
UniProt Gene Name
GPR126 [Similar Products]
UniProt Synonym Gene Names
DREG; VIGR [Similar Products]
UniProt Entry Name
GP126_HUMAN
NCBI Summary for GPR126
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for GPR126
GPR126: Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 2
Chromosomal Location of Human Ortholog: 6q24.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on GPR126
1. Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
