Product Name
SLC29A3, Polyclonal Antibody
Full Product Name
SLC29A3
Product Synonym Names
ENT3; HCLAP; HJCD; PHID
Product Gene Name
anti-SLC29A3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BZD2
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human SLC29A3
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-SLC29A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC29A3 antibody
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.
Applications Tested/Suitable for anti-SLC29A3 antibody
Western Blot (WB)
Application Notes for anti-SLC29A3 antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for SLC29A3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001167569.1
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NCBI GenBank Nucleotide #
NM_001174098.1
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UniProt Primary Accession #
Q9BZD2
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UniProt Secondary Accession #
Q0VAM9; Q5T465; Q7RTT8; Q8IVZ0; Q9BWI2; Q9NUS9; B2RB50; B4E2Z9; B7ZA37[Other Products]
UniProt Related Accession #
Q9BZD2[Other Products]
NCBI Official Full Name
equilibrative nucleoside transporter 3 isoform b
NCBI Official Synonym Full Names
solute carrier family 29 member 3
NCBI Official Symbol
SLC29A3 [Similar Products]
NCBI Official Synonym Symbols
ENT3; HJCD; PHID; HCLAP
[Similar Products]
NCBI Protein Information
equilibrative nucleoside transporter 3
UniProt Protein Name
Equilibrative nucleoside transporter 3
UniProt Synonym Protein Names
Solute carrier family 29 member 3
Protein Family
Equilibrative nucleoside transporter
UniProt Gene Name
SLC29A3 [Similar Products]
UniProt Synonym Gene Names
ENT3; hENT3 [Similar Products]
NCBI Summary for SLC29A3
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010]
UniProt Comments for SLC29A3
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.
Research Articles on SLC29A3
1. C predicted to cause a splicing error. Patients with similar mutations are reviewed.">In a patient with H syndrome, a compound heterozygous alteration in the SLC29A3 gene was found. Her parents each had one of the mutations. The c.243delA frameshift mutation leading to a premature termination, resulting in a truncated protein, and a splice site mutation c.300+1G>C predicted to cause a splicing error. Patients with similar mutations are reviewed.
Precautions
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Disclaimer
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