Full Product Name
KCNV2 Antibody
Product Gene Name
anti-KCNV2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-KCNV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KCNV2 antibody
Rabbit polyclonal KCNV2 (1) antibody was raised against a recombinate human KCNV2 protein 12-154aa (BC101352).
Product Categories/Family for anti-KCNV2 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-KCNV2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-KCNV2 antibody
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
Testing Data of anti-KCNV2 antibody
NCBI/Uniprot data below describe general gene information for KCNV2. It may not necessarily be applicable to this product.
NCBI Accession #
BC101352
[Other Products]
UniProt Secondary Accession #
Q5T6X0[Other Products]
UniProt Related Accession #
Q8TDN2[Other Products]
Molecular Weight
62,459 Da
NCBI Official Full Name
Homo sapiens potassium channel, subfamily V, member 2, mRNA
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily V member 2
NCBI Official Symbol
KCNV2 [Similar Products]
NCBI Official Synonym Symbols
Kv8.2; RCD3B; KV11.1
[Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily V member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily V member 2
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv8.2
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNV2 [Similar Products]
NCBI Summary for KCNV2
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNV2
Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Product References and Citations for anti-KCNV2 antibody
(1) Jorge, B.S., Campbell, C.M., Miller, A.R. et al. Voltage-gated potassium channel KCNV2 (Kv8.2) contributes to epilepsy susceptibility. Proc. Natl. Acad. Sci. U.S.A. 108 (13), 5443-5448 (2011).
Research Articles on KCNV2
1. Pharmacogenetic and case-control study evaluated the role of the variants of KCNA1, KCNA2, and KCNV2 in the susceptibility and drug resistance of genetic generalized epilepsies and revealed no significant association between 8 variants of KCNA1, KCNA2, and KCNV2 genes and risk or drug resistance of genetic generalized epilepsies after a Bonferroni correction for multiple comparisons.
Precautions
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Disclaimer
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