KCNV2, Antibody

KCNV2; potassium voltage-gated channel subfamily V member 2; voltage-gated potassium channel subunit Kv8.2

For Research Use Only. Not for use in diagnostic procedures.

KCNV2 Antibody detects endogenous levels of total KCNV2

Immunogen affinity purified

In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at-20 degree C. Stable for 12 months from date of receipt.

Small volumes of anti-KCNV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB)

WB: 1:500-1:1000

Western blot analysis of extracts from MCF-7 cells, using KCNV2 antibody.

62 KD

potassium voltage-gated channel modifier subfamily V member 2

potassium voltage-gated channel subfamily V member 2

Potassium voltage-gated channel subfamily V member 2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.

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