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Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody

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产品名称: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody
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简单介绍

Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody


Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody  的详细介绍
Product Name

Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1)

Product Gene Name

anti-FGFRL1 antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2005122)
Immunogen: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2012389)
Matching Pairs
Unconjugated Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2005122)
APC-CY7 Conjugated Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2082587)
Matching Pairs
Unconjugated Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2005122)
PE Conjugated Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2082588)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-VRL KCVA SGHPRPDIMW MKDDQTLTHL EASEHRKKKW TLSLKNLKPE DSGKYTCRVS NKAGAINATY KVDVIQRTRS KPVLTGTHPV NTTVDFGGTT SFQCKVRSDV KPVIQWLKRV EYGSEGRHNS TIDVGGQKFV VLPTGDVWSR PDGSYLNKLL ISRARQDDAG MYICLGANTM GYSFRSAFLT VLPDPKPPGP PMASSSSSTS LPWP
3D Structure
ModBase 3D Structure for Q91V87
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against FGFRL1. It has been selected for its ability to recognize FGFRL1 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
200ug/ml (lot specific)
Immunogen
Recombinant FGFRL1 (Val164~Pro374) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2082589
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-FGFRL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-FGFRL1 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-FGFRL1 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-FGFRL1 antibody
Western Blot: Sample: Mouse Kidney lysate; Primary Ab: 5ug/ml Rabbit Anti-Mouse FGFRL1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-FGFRL1 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-FGFRL1 antibody
Western Blot: Sample: Recombinant protein.
anti-FGFRL1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-FGFRL1 antibody
DAB staining on IHC-P. Samples: Mouse Tissue)
anti-FGFRL1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for FGFRL1. It may not necessarily be applicable to this product.
NCBI GI #
256000817
NCBI GeneID
116701
NCBI Accession #
NP_001157731.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001164259.1 [Other Products]
UniProt Primary Accession #
Q91V87 [Other Products]
UniProt Secondary Accession #
Q920C2; Q920C3[Other Products]
UniProt Related Accession #
Q91V87[Other Products]
Molecular Weight
46,981 Da
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NCBI Official Full Name
fibroblast growth factor receptor-like 1 isoform 2
NCBI Official Synonym Full Names
fibroblast growth factor receptor-like 1
NCBI Official Symbol
Fgfrl1  [Similar Products]
NCBI Official Synonym Symbols
FGFR5; FGFR5beta; FGFR5gamma
  [Similar Products]
NCBI Protein Information
fibroblast growth factor receptor-like 1
UniProt Protein Name
Fibroblast growth factor receptor-like 1
UniProt Synonym Protein Names
Fibroblast growth factor receptor 5; FGFR-5
Protein Family
Fibroblast growth factor receptor
UniProt Gene Name
Fgfrl1  [Similar Products]
UniProt Synonym Gene Names
Fgfr5; FGF receptor-like protein 1; FGFR-5  [Similar Products]
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UniProt Comments for FGFRL1
FGFRL1: Has a negative effect on cell proliferation.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5|5 F

Cellular Component: Golgi apparatus; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane; transport vesicle

Molecular Function: fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; heparin binding; non-tyrosine kinase fibroblast growth factor receptor activity

Biological Process: cell surface receptor signaling pathway; negative regulation of cell proliferation; negative regulation of fibroblast growth factor receptor signaling pathway; protein homooligomerization; skeletal system development
Research Articles on FGFRL1
1. FGFRL1 contains three extracellular Ig-like domains and a single transmembrane domain. It lacks the intracellular tyrosine kinase domain, but contains a short intracellular tail with a peculiar histidine-rich motif.The reason why this motif was conserved during evolution in most species, but not in mice, is not clear.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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