Product Name
Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1), Antibody Pair Kit
Full Product Name
Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Antibody Pair Kit (with Standard)
Product Synonym Names
FGFR5; FHFR; FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5
Product Gene Name
FGFRL1 antibody pair kit
[Similar Products]
Matching Pairs
Antibody: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2104216)
Pairing: Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) (MBS2104216)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q8N441
Samples
Tissue Homogenates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant FGFRL1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of FGFRL1 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for FGFRL1 antibody pair kit
CD & Adhesion molecule
Applications Tested/Suitable for FGFRL1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for FGFRL1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001004356.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001004356.2
[Other Products]
UniProt Primary Accession #
Q8N441
[Other Products]
UniProt Secondary Accession #
Q6PJN1; Q9BXN7; Q9H4D7; B2RAU9[Other Products]
UniProt Related Accession #
Q8N441[Other Products]
Molecular Weight
54,537 Da
NCBI Official Full Name
fibroblast growth factor receptor-like 1
NCBI Official Synonym Full Names
fibroblast growth factor receptor like 1
NCBI Official Symbol
FGFRL1 [Similar Products]
NCBI Official Synonym Symbols
FHFR; FGFR5
[Similar Products]
NCBI Protein Information
fibroblast growth factor receptor-like 1
UniProt Protein Name
Fibroblast growth factor receptor-like 1
UniProt Synonym Protein Names
FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5; FGFR-5
Protein Family
Fibroblast growth factor receptor
UniProt Gene Name
FGFRL1 [Similar Products]
UniProt Synonym Gene Names
FGFR5; FHFR; FGF receptor-like protein 1; FGFR-5 [Similar Products]
NCBI Summary for FGFRL1
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FGFRL1
Has a negative effect on cell proliferation.
Research Articles on FGFRL1
1. FGFRL1 is a transmembrane receptor that can induce the fusion of CHO cells to multinucleated syncytia. This cell fusion activity has been attributed to the extracellular Ig3 domain of the receptor. The Ig3 domain from humans, mice, chicken and fish stimulates fusion of CHO cells, while the Ig3 domain from lancelet and sea urchin does not.
Precautions
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Disclaimer
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