Product Name
ERAB/HCD2, Polyclonal Antibody
Full Product Name
ERAB / HCD2 Antibody
Product Synonym Names
3-hydroxyacyl-CoA dehydrogenase type-2
Product Gene Name
anti-ERAB/HCD2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O70351
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-ERAB/HCD2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (lot specific)
Immunogen
Synthetic peptide surrounding amino acid 250 of rat ERAB/HCD2
Positive Control
Rat kidney tissue lysate, mouse 3T3 cell lysate, and Jurkat cell lysate
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of anti-ERAB/HCD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ERAB/HCD2 antibody
Background: ERAB/HCD2 (Hydroxyacyl-Coenzyme A dehydrogenase) is a mitochondrial protein that catalyzes the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. ERAB is characterized as a NAD+-dependent dehydrogenase that overexpressed in neurons affected with Alzheimer's disease.
Product Categories/Family for anti-ERAB/HCD2 antibody
Diabetes, Obesity & Metabolic Syndrome; Lipid Metabolism; AntibodiesAntibodies & Supporting Tools; Primary Antibodies (A-Z)
Applications Tested/Suitable for anti-ERAB/HCD2 antibody
Western Blot (WB)
Application Notes for anti-ERAB/HCD2 antibody
The antibody can be used for Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately.
Testing Data of anti-ERAB/HCD2 antibody
NCBI/Uniprot data below describe general gene information for ERAB/HCD2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_113870.1
[Other Products]
NCBI GenBank Nucleotide #
NM_031682.1
[Other Products]
UniProt Primary Accession #
O70351
[Other Products]
UniProt Secondary Accession #
Q9QYD4[Other Products]
UniProt Related Accession #
O70351[Other Products]
Molecular Weight
27,246 Da
NCBI Official Full Name
3-hydroxyacyl-CoA dehydrogenase type-2
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 10
NCBI Official Symbol
Hsd17b10 [Similar Products]
NCBI Official Synonym Symbols
Hadh2
[Similar Products]
NCBI Protein Information
3-hydroxyacyl-CoA dehydrogenase type-2
UniProt Protein Name
3-hydroxyacyl-CoA dehydrogenase type-2
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase 10 (EC:1.1.1.51); 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC:1.1.1.178); 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Type II HADH
UniProt Gene Name
Hsd17b10 [Similar Products]
UniProt Synonym Gene Names
Erab; Hadh2; 17-beta-HSD 10; Mitochondrial RNase P protein 2 [Similar Products]
UniProt Entry Name
HCD2_RAT
NCBI Summary for ERAB/HCD2
a type 10 17beta-hydroxysteroid dehydrogenase enzyme of the mitochondria [RGD, Feb 2006]
UniProt Comments for ERAB/HCD2
HADH2: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends (By similarity)
Protein type: Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178; Oxidoreductase
Research Articles on ERAB/HCD2
1. that 17beta-HSD-10 is a major product of both fetal and *****-type Leydig cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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