Full Product Name
KV8.2 Polyclonal Antibody
Product Gene Name
anti-KV8.2 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8TDN2
Other Notes
Small volumes of anti-KV8.2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for KV8.2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_598004.1
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NCBI GenBank Nucleotide #
NM_133497.3
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UniProt Primary Accession #
Q8TDN2
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UniProt Secondary Accession #
Q5T6X0[Other Products]
UniProt Related Accession #
Q8TDN2[Other Products]
Molecular Weight
62,459 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily V member 2
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily V member 2
NCBI Official Symbol
KCNV2 [Similar Products]
NCBI Official Synonym Symbols
Kv8.2; RCD3B; KV11.1
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NCBI Protein Information
potassium voltage-gated channel subfamily V member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily V member 2
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv8.2
UniProt Gene Name
KCNV2 [Similar Products]
NCBI Summary for KV8.2
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]
UniProt Comments for KV8.2
Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Research Articles on KV8.2
1. Pharmacogenetic and case-control study evaluated the role of the variants of KCNA1, KCNA2, and KCNV2 in the susceptibility and drug resistance of genetic generalized epilepsies and revealed no significant association between 8 variants of KCNA1, KCNA2, and KCNV2 genes and risk or drug resistance of genetic generalized epilepsies after a Bonferroni correction for multiple comparisons.
Precautions
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Disclaimer
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