5HT1A, Polyclonal Antibody

ADRBRL1; G 21; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; HTR1A; PFMCD antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

This antibody will only detect Annexin A1 protien. The antibody will detect solute Annexin A1.

BIOTIN-Conjugated Immunoglobulins

0.75 mg/ml IgG in antibody stabilization buffer (lot specific)

-20 degree C for long term storage

Small volumes of anti-5HT1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

BIOTIN-Conjugated 5 Hydroxytryptamine 1A receptor Antibody
G-protein coupled receptor for serotonin (5-hydroxytryptamine). Functions as a receptor for various drugs which cause conformational change upon ligand binding that triggers signaling via guanine nucleo-tide binding proteins and modulation of down-stream effectors like adenylate cyclase. Inhibits adenylate cyclase activity and activates phosphatidylinositol-calcium second messenger system that regulates release of intracellular Calcium ions.

ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)

Dot Blot: 1:50,000
ELISA: 1:50,000
Immunoprecipitation: 1:200
Western Blot: 1:2,500-1:5,000

46,429 Da

5-hydroxytryptamine receptor 1A

5-hydroxytryptamine receptor 1A

5-hydroxytryptamine receptor 1A

5ht1a; 5-HT-1A; 5-HT1A  [Similar Products]

5HT1A_RAT

regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD, Feb 2006]

5-HT(1A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. 5- hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Cellular Component: axon hillock; cell soma; integral to plasma membrane; membrane

Molecular Function: drug binding; G-protein alpha-subunit binding; protein binding; serotonin binding; serotonin receptor activity

Biological Process: behavioral fear response; cell proliferation; G-protein coupled receptor protein signaling pathway; positive regulation of microtubule depolymerization; regulation of behavior; regulation of dopamine metabolic process; regulation of hormone secretion; regulation of serotonin secretion; serotonin metabolic process; serotonin receptor signaling pathway; serotonin receptor, adenylate cyclase inhibiting pathway; vasoconstriction

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