Product Name
IRX1, Blocking Peptide
Full Product Name
IRX1 Peptide - middle region
Product Gene Name
IRX1 blocking peptide
[Similar Products]
Product Synonym Gene Name
IRX-5; IRXA1[Similar Products]
IRX1 peptide (MBS3233670) is used for blocking the activity of IRX1 antibody (MBS3208708)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78414
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of IRX1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
IRX1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-IRX1 antibody made
Target Description: IRX1 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.
Product Categories/Family for IRX1 blocking peptide
Peptide
Applications Tested/Suitable for IRX1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for IRX1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_077313
[Other Products]
NCBI GenBank Nucleotide #
NM_024337
[Other Products]
UniProt Primary Accession #
P78414
[Other Products]
UniProt Related Accession #
P78414[Other Products]
NCBI Official Full Name
iroquois-class homeodomain protein IRX-1
NCBI Official Synonym Full Names
iroquois homeobox 1
NCBI Official Symbol
IRX1 [Similar Products]
NCBI Official Synonym Symbols
IRX-5; IRXA1
[Similar Products]
NCBI Protein Information
iroquois-class homeodomain protein IRX-1
UniProt Protein Name
Iroquois-class homeodomain protein IRX-1
UniProt Synonym Protein Names
Homeodomain protein IRXA1; Iroquois homeobox protein 1
Protein Family
Iroquois-class homeodomain protein
UniProt Gene Name
IRX1 [Similar Products]
UniProt Synonym Gene Names
IRXA1 [Similar Products]
UniProt Entry Name
IRX1_HUMAN
NCBI Summary for IRX1
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011]
UniProt Comments for IRX1
IRX1: a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011]
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 5p15.3
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: regulation of transcription, DNA-dependent
Research Articles on IRX1
1. Through a combination of sequencing studies on eighteen North Carolina macular dystrophy families, two novel overlapping duplications at the MCDR3 locus, in a gene desert downstream of IRX1 and upstream of ADAMTS16, have been reported.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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