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Delta Opioid Receptor, Polyclonal Antibody

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产品名称: Delta Opioid Receptor, Polyclonal Antibody
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简单介绍

Delta Opioid Receptor, Polyclonal Antibody


Delta Opioid Receptor, Polyclonal Antibody  的详细介绍
Product Name

Delta Opioid Receptor (OPRD1), Polyclonal Antibody

Popular Item
Full Product Name

Anti-Delta Opioid Receptor Antibody

Product Synonym Names
OPRD; Delta-type opioid receptor; D-OR-1; DOR-1
Product Gene Name

anti-OPRD1 antibody

[Similar Products]
Antibody/Peptide Pairs
Delta Opioid Receptor peptide (MBS822543) is used for blocking the activity of Delta Opioid Receptor antibody (MBS821946)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
165195
3D Structure
ModBase 3D Structure for P41143
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Pig
Specificity
Recognizes endogenous levels of Delta Opioid Receptor protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Entrez Gene
4985 (HUMAN); 18386 (MOUSE); 24613 (RAT)
SwissProt
P41143 (HUMAN;P32300(MOUSE); P33533 (RAT)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Delta Opioid Receptor. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-OPRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-OPRD1 antibody
Rabbit polyclonal antibody to Delta Opioid Receptor
Applications Tested/Suitable for anti-OPRD1 antibody
Western Blot (WB)
Application Notes for anti-OPRD1 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-OPRD1 antibody
Western blot analysis of Delta Opioid Receptor expression in human brain (A), mouse brain (B), rat brain (C) whole cell lysates.
anti-OPRD1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-OPRD1 antibody

anti-OPRD1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for OPRD1. It may not necessarily be applicable to this product.
NCBI GI #
63477962
NCBI GeneID
4985
NCBI Accession #
NP_000902.3 [Other Products]
NCBI GenBank Nucleotide #
NM_000911.3 [Other Products]
UniProt Primary Accession #
P41143 [Other Products]
UniProt Secondary Accession #
B5B0B8[Other Products]
UniProt Related Accession #
P41143[Other Products]
Molecular Weight
40,369 Da
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NCBI Official Full Name
delta-type opioid receptor
NCBI Official Synonym Full Names
opioid receptor, delta 1
NCBI Official Symbol
OPRD1  [Similar Products]
NCBI Official Synonym Symbols
OPRD
  [Similar Products]
NCBI Protein Information
delta-type opioid receptor; DOR-1; D-OR-1; delta opioid receptor 1
UniProt Protein Name
Delta-type opioid receptor
Protein Family
Delta-type opioid receptor
UniProt Gene Name
OPRD1  [Similar Products]
UniProt Synonym Gene Names
OPRD; D-OR-1; DOR-1  [Similar Products]
UniProt Entry Name
OPRD_HUMAN
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UniProt Comments for OPRD1
DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: postsynaptic membrane; neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; vesicle; intrinsic to plasma membrane; lipid raft

Molecular Function: neuropeptide binding; protein binding; opioid receptor activity

Biological Process: ***** locomotory behavior; activation of CREB transcription factor; regulation of calcium ion transport; sensory perception of pain; positive regulation of peptidyl-serine phosphorylation; G-protein coupled receptor protein signaling pathway; synaptic transmission; negative regulation of protein oligomerization; G-protein signaling, coupled to cyclic nucleotide second messenger; regulation of mitochondrial membrane potential; protein import into nucleus, translocation; neuropeptide signaling pathway; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway
Research Articles on OPRD1
1. OPRD1 rs678849 polymorphism was associated with reduced brain volumes in young participants and elderly Alzheimer's Disease and Mild Cognitive Impairment patients, but brain regions affected differed
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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