Product Name
Multiple PDZ domain protein (MPDZ), Recombinant Protein
Full Product Name
Recombinant Human Multiple PDZ domain protein (MPDZ) , partial
Product Gene Name
MPDZ recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75970
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of MPDZ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MPDZ. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001248335.1
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NCBI GenBank Nucleotide #
NM_001261406.1
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UniProt Primary Accession #
O75970
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UniProt Secondary Accession #
O43798; Q4LE30; Q5CZ80; Q5JTX3; Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; A6NLC2; B2RTS3; B7ZMI4[Other Products]
UniProt Related Accession #
O75970[Other Products]
Molecular Weight
214,804 Da
NCBI Official Full Name
multiple PDZ domain protein isoform 2
NCBI Official Synonym Full Names
multiple PDZ domain crumbs cell polarity complex component
NCBI Official Symbol
MPDZ [Similar Products]
NCBI Official Synonym Symbols
HYC2; MUPP1
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NCBI Protein Information
multiple PDZ domain protein
UniProt Protein Name
Multiple PDZ domain protein
UniProt Synonym Protein Names
Multi-PDZ domain protein 1
Protein Family
Multiple PDZ domain protein
UniProt Gene Name
MPDZ [Similar Products]
UniProt Synonym Gene Names
MUPP1 [Similar Products]
NCBI Summary for MPDZ
The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt Comments for MPDZ
Interacts with HTR2C and provokes its clustering at the cell surface (). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.
Research Articles on MPDZ
1. two peptides (SIAPNV(-COOH) and SIVMNV(-COOH)) were identified to have considerably improved affinity with K d increase by ~tenfold relative to wild type peptide. Thus, the two peptides are considered as promising lead entities to develop therapeutic molecular agents with high efficacy and specificity to target CaMKIIalpha-MUPP1 interaction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
