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Carboxypeptidase A1, Blocking Peptide

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产品名称: Carboxypeptidase A1, Blocking Peptide
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简单介绍

Carboxypeptidase A1, Blocking Peptide


Carboxypeptidase A1, Blocking Peptide  的详细介绍
Product Name

Carboxypeptidase A1 (CPA1), Blocking Peptide

Full Product Name

Carboxypeptidase A1 Blocking Peptide

Product Synonym Names
CPA; Carboxypeptidase A1
Product Gene Name

CPA1 blocking peptide

[Similar Products]
Antibody/Peptide Pairs
Carboxypeptidase A1 peptide (MBS824305) is used for blocking the activity of Carboxypeptidase A1 antibody (MBS820217)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
114850
3D Structure
ModBase 3D Structure for P15085
Host
Synthetic
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of CPA1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
CPA1 blocking peptide
The peptide is used to block Anti-Carboxypeptidase A1 Antibody reactivity.
Applications Tested/Suitable for CPA1 blocking peptide
Blocking (BL)
Application Notes for CPA1 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for CPA1. It may not necessarily be applicable to this product.
NCBI GI #
4502997
NCBI GeneID
1357
NCBI Accession #
NP_001859.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001868.2 [Other Products]
UniProt Primary Accession #
P15085 [Other Products]
UniProt Secondary Accession #
Q53XU0; Q9BS67; Q9UCF2; A4D1M1[Other Products]
UniProt Related Accession #
P15085[Other Products]
Molecular Weight
47,140 Da
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NCBI Official Full Name
carboxypeptidase A1
NCBI Official Synonym Full Names
carboxypeptidase A1 (pancreatic)
NCBI Official Symbol
CPA1  [Similar Products]
NCBI Official Synonym Symbols
CPA
  [Similar Products]
NCBI Protein Information
carboxypeptidase A1; pancreatic carboxypeptidase A
UniProt Protein Name
Carboxypeptidase A1
Protein Family
Carboxypeptidase
UniProt Gene Name
CPA1  [Similar Products]
UniProt Synonym Gene Names
CPA  [Similar Products]
UniProt Entry Name
CBPA1_HUMAN
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NCBI Summary for CPA1
Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition. [provided by RefSeq, Jan 2009]
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UniProt Comments for CPA1
CPA1: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Belongs to the peptidase M14 family.

Protein type: Secreted; EC 3.4.17.1; Secreted, signal peptide; Protease

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: extracellular space

Molecular Function: zinc ion binding; metallocarboxypeptidase activity

Biological Process: proteolysis
Research Articles on CPA1
1. mechanism by which CPA1 variants confer increased pancreatitis risk may involve misfolding-induced endoplasmic reticulum stress rather than elevated trypsin activity
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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