ABCD1, Polyclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Purified by protein A column containing 0.02% NaN3

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Small volumes of anti-ABCD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Rabbit polyclonal ABCD1 (1) antibody was raised against a recombinate human ABCD1 protein 560-737aa (NM_000033).

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-500

82,937 Da

ATP binding cassette subfamily D member 1

ATP-binding cassette sub-family D member 1

ATP-binding cassette sub-family D member 1

ALD; ALDP  [Similar Products]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]

Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.

(1) Hour, T.C., Kuo, Y.Z., Liu, G.Y., Kang, W.Y., et al. Downregulation of ABCD1 in human renal cell carcinoma. Int. J. Biol. Markers 24 (3), 171-178 (2009).

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