Full Product Name
HSF4 Antibody
Product Synonym Names
CTM; CTRCT5
Product Gene Name
anti-HSF4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9ULV5
Species Reactivity
Human, Mouse
Specificity
The antibody detects endogenous levels of total HSF4 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3mg/ml (lot specific)
Immunogen
Synthetic peptide corresponding to internal residues of human HSF4
Preparation and Storage
Store at -20 degree C.
Other Notes
Small volumes of anti-HSF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HSF4 antibody
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Product Categories/Family for anti-HSF4 antibody
Total protein Ab
Applications Tested/Suitable for anti-HSF4 antibody
Immunohistochemistry (IHC)
Application Notes for anti-HSF4 antibody
IHC: 1: 40-200
Immunohistochemistry (IHC) of anti-HSF4 antibody
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 46581(HSF4 Antibody) at dilution 1/55, on the right is treated with synthetic peptide. (Original magnification: x200)
NCBI/Uniprot data below describe general gene information for HSF4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001529
[Other Products]
NCBI GenBank Nucleotide #
NM_001538.3
[Other Products]
UniProt Primary Accession #
Q9ULV5
[Other Products]
UniProt Secondary Accession #
Q99472; Q9ULV6[Other Products]
UniProt Related Accession #
Q9ULV5[Other Products]
Molecular Weight
49,952 Da
NCBI Official Full Name
heat shock factor protein 4 isoform a
NCBI Official Synonym Full Names
heat shock transcription factor 4
NCBI Official Symbol
HSF4 [Similar Products]
NCBI Official Synonym Symbols
CTM; CTRCT5
[Similar Products]
NCBI Protein Information
heat shock factor protein 4
UniProt Protein Name
Heat shock factor protein 4
UniProt Synonym Protein Names
Heat shock transcription factor 4; HSTF 4
Protein Family
Heat shock factor protein
UniProt Gene Name
HSF4 [Similar Products]
UniProt Synonym Gene Names
HSF 4; hHSF4; HSTF 4 [Similar Products]
NCBI Summary for HSF4
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for HSF4
DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.
Research Articles on HSF4
1. C, p.Leu174Pro) in two sibs with congenital cataracts">report on a novel homozygous HSF4 mutation (c.521T>C, p.Leu174Pro) in two sibs with congenital cataracts
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
