beta III Tubulin, Polyclonal Antibody

beta-4; tubulin beta-4; Tubulin beta-4 chain; Tubulin beta-III; CFEOM3A; MC1R; TBB3; TUBB3; TUBB4; Tubulin beta-3 chain; tubulin; beta 3; tubulin; beta; 4; beta tubulin

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

beta III Tubulin Antibody detects endogenous levels of total beta Tubulin III

Affinity Chromatography

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Small volumes of anti-TUBB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

TUBB3 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)

WB: 1:5000-1:10000
IHC: 1:50-1:200
ICC: 1:50-1:200
IP: 1:50
FC/FACS: 1:50

Western blot analysis of beta III Tubulin expression in HeLa cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer, using beta III Tubulin Antibody.

Immunofluorescent analysis of PC12 cells, using beta III Tubulin Antibody.

55kDa[Similar Products]

tubulin beta 3 class III

tubulin beta-3 chain

Tubulin beta-3 chain

TUBB4  [Similar Products]

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

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