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CIZ1, Polyclonal Antibody

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产品名称: CIZ1, Polyclonal Antibody
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简单介绍

CIZ1, Polyclonal Antibody


CIZ1, Polyclonal Antibody  的详细介绍
Product Name

CIZ1, Polyclonal Antibody

Full Product Name

CIZ1 Polyclonal Antibody

Product Synonym Names
NP94; LSFR1; ZNF356
Product Gene Name

anti-CIZ1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
611420
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.4mg/mL (lot specific)
Immunogen
Synthetic peptide of human CIZ1
Calculated Molecular Weight: 100kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CIZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-CIZ1 antibody
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-CIZ1 antibody
Cell biology
Applications Tested/Suitable for anti-CIZ1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CIZ1 antibody
WB: 1:200-1:1000

Western Blot (WB) of anti-CIZ1 antibody
Western Blot analysis of A549 cell using CIZ1 Polyclonal Antibody at dilution of 1:200
anti-CIZ1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CIZ1. It may not necessarily be applicable to this product.
NCBI GI #
384081602
NCBI GeneID
25792
NCBI Accession #
NP_001244905.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001257976.1 [Other Products]
UniProt Secondary Accession #
Q5SYW3; Q5SYW5; Q8WU72; Q9H868; Q9NYM8; Q9UHK4; Q9Y3F9; Q9Y3G0; A8K9J8; B4E131; B7ZAS8[Other Products]
UniProt Related Accession #
Q9ULV3[Other Products]
Molecular Weight
88,520 Da
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NCBI Official Full Name
cip1-interacting zinc finger protein isoform 6
NCBI Official Synonym Full Names
CDKN1A interacting zinc finger protein 1
NCBI Official Symbol
CIZ1  [Similar Products]
NCBI Official Synonym Symbols
NP94; LSFR1; ZNF356
  [Similar Products]
NCBI Protein Information
cip1-interacting zinc finger protein; nuclear protein NP94; zinc finger protein 356
UniProt Protein Name
Cip1-interacting zinc finger protein
UniProt Synonym Protein Names
CDKN1A-interacting zinc finger protein 1; Nuclear protein NP94; Zinc finger protein 356
Protein Family
Cip1-interacting zinc finger protein
UniProt Gene Name
CIZ1  [Similar Products]
UniProt Synonym Gene Names
LSFR1; NP94; ZNF356  [Similar Products]
UniProt Entry Name
CIZ1_HUMAN
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NCBI Summary for CIZ1
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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UniProt Comments for CIZ1
CIZ1: May regulate the subcellular localization of CIP/WAF1. Defects in CIZ1 may be a cause of ***** onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: nucleus

Molecular Function: protein binding; nucleic acid binding; zinc ion binding
Research Articles on CIZ1
1. This study suggested that No mutations in CIZ1 in twelve *****-onset primary cervical dystonia families.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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