Product Name
CIZ1, Blocking Peptide
Full Product Name
CIZ1 Immunizing Peptide
Product Synonym Names
CIZ1; CDKN1A interacting zinc finger protein 1; LSFR1; NP94; ZNF356; CDKN1A-interacting zinc finger protein 1; cip1-interacting zinc finger protein; nuclear protein NP94; zinc finger protein 356
Product Gene Name
CIZ1 blocking peptide
[Similar Products]
CIZ1 peptide (MBS428430) is used for blocking the activity of CIZ1 antibody (MBS423340)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-QPNTQDKT PSKVTAR
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CIZ1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CIZ1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036259.2
[Other Products]
NCBI Related Accession #
Manufactured in an ISO 9001:2008 Certified Laboratory.NP_001124487.1; NP_001124489.1; NP_001124490.1; NP_001244904.1; NP_001244905.1[Other Products]
NCBI GenBank Nucleotide #
NM_012127.2
[Other Products]
UniProt Secondary Accession #
Q5SYW3; Q5SYW5; Q8WU72; Q9H868; Q9NYM8; Q9UHK4; Q9Y3F9; Q9Y3G0; A8K9J8; B4E131; B7ZAS8[Other Products]
UniProt Related Accession #
Q9ULV3[Other Products]
Molecular Weight
88,520 Da
NCBI Official Full Name
cip1-interacting zinc finger protein isoform 1
NCBI Official Synonym Full Names
CDKN1A interacting zinc finger protein 1
NCBI Official Symbol
CIZ1 [Similar Products]
NCBI Official Synonym Symbols
NP94; LSFR1; ZNF356
[Similar Products]
NCBI Protein Information
cip1-interacting zinc finger protein
UniProt Protein Name
Cip1-interacting zinc finger protein
UniProt Synonym Protein Names
CDKN1A-interacting zinc finger protein 1; Nuclear protein NP94; Zinc finger protein 356
Protein Family
Cip1-interacting zinc finger protein
UniProt Gene Name
CIZ1 [Similar Products]
UniProt Synonym Gene Names
LSFR1; NP94; ZNF356 [Similar Products]
UniProt Entry Name
CIZ1_HUMAN
NCBI Summary for CIZ1
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
UniProt Comments for CIZ1
CIZ1: May regulate the subcellular localization of CIP/WAF1. Defects in CIZ1 may be a cause of ***** onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 9q34.1
Cellular Component: nucleus
Molecular Function: nucleic acid binding; protein binding; zinc ion binding
Research Articles on CIZ1
1. CIZ1 is a kinase sensor that promotes initiation of DNA replication at low kinase levels, when in a hypophosphorylated state that is permissive for cyclin-A-CDK2 interaction and delivery to licensed origins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.