SLC34A3, Polyclonal Antibody

Sodium-dependent phosphate transport protein 2C; Sodium-phosphate transport protein 2C; Na(+)-dependent phosphate cotransporter 2C; Sodium/inorganic phosphate cotransporter IIC; Sodium/phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; NaPi-2c; Solute carrier family 34 member 3; SLC34A3; NPT2C; NPTIIC

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

>95%, Protein G purified

Liquid

Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of anti-SLC34A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.

Metabolism; Signal transduction

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

IHC: 1:200-1:500
IF: 1:50-1:200

IHC image of MBS7108535 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of Hela cells with MBS7108535 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

63,550 Da

solute carrier family 34 member 3

sodium-dependent phosphate transport protein 2C

Sodium-dependent phosphate transport protein 2C

NPT2C; NPTIIC; Sodium-phosphate transport protein 2C; Na(+)/Pi cotransporter 2C; NaPi-2c  [Similar Products]

This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.[provided by RefSeq, Apr 2010]

May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.

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