Product Name
AKAP3, Blocking Peptide
Full Product Name
AKAP3 Antibody (Center) Blocking Peptide
Product Synonym Names
A-kinase anchor protein 3; AKAP-3; A-kinase anchor protein 110 kDa; AKAP 110; Cancer/testis antigen 82; CT82; Fibrous sheath protein of 95 kDa; FSP95; Fibrousheathin I; Fibrousheathin-1; Protein kinase A-anchoring protein 3; PRKA3; Sperm oocyte-binding protein; AKAP3; AKAP110; SOB1
Product Gene Name
AKAP3 blocking peptide
[Similar Products]
Product Synonym Gene Name
AKAP110; SOB1[Similar Products]
Antibody/Peptide Pairs
AKAP3 peptide (MBS9227676) is used for blocking the activity of AKAP3 antibody (MBS9201172)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75969
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human AKAP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Note: Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment
Tissue Location
Testis specific; only expressed in spermatids.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of AKAP3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AKAP3 blocking peptide
May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.
NCBI/Uniprot data below describe general gene information for AKAP3. It may not necessarily be applicable to this product.
NCBI Accession #
O75969.2
[Other Products]
UniProt Primary Accession #
O75969
[Other Products]
UniProt Secondary Accession #
O75945; Q86X01; Q9UM61[Other Products]
UniProt Related Accession #
O75969[Other Products]
Molecular Weight
94,751 Da
NCBI Official Full Name
A-kinase anchor protein 3
NCBI Official Synonym Full Names
A-kinase anchoring protein 3
NCBI Official Symbol
AKAP3 [Similar Products]
NCBI Official Synonym Symbols
CT82; SOB1; FSP95; PRKA3; HEL159; AKAP110; AKAP 110
[Similar Products]
NCBI Protein Information
A-kinase anchor protein 3
UniProt Protein Name
A-kinase anchor protein 3
UniProt Synonym Protein Names
A-kinase anchor protein 110 kDa; AKAP 110; Cancer/testis antigen 82; CT82; Fibrous sheath protein of 95 kDa; FSP95; Fibrousheathin I; Fibrousheathin-1; Protein kinase A-anchoring protein 3; PRKA3; Sperm oocyte-binding protein
Protein Family
A-kinase anchor protein
UniProt Gene Name
AKAP3 [Similar Products]
UniProt Synonym Gene Names
AKAP110; SOB1; AKAP-3; AKAP 110; CT82; FSP95; PRKA3 [Similar Products]
UniProt Entry Name
AKAP3_HUMAN
NCBI Summary for AKAP3
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013]
UniProt Comments for AKAP3
AKAP3: May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Belongs to the AKAP110 family.
Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: acrosome reaction; cell motility; single fertilization
Research Articles on AKAP3
1. AKAP3 correlates with triple negative status and disease free survival in breast cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
