Product Name
Conserved oligomeric Golgi complex subunit 4 (COG4), Recombinant Protein
Full Product Name
Recombinant Human Conserved oligomeric Golgi complex subunit 4 (COG4)
Product Gene Name
COG4 recombinant protein
[Similar Products]
Product Synonym Gene Name
COG4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-785aa, Full Length of Mature Protein
Sequence
ADLDSPPKLS GVQQPSEGVG GGRCSEISAE LIRSLTELQE LEAVYERLCG EEKVVERELD ALLEQQNTIE SKMVTLHRMG PNLQLIEGDA KQLAGMITFT CNLAENVSSK VRQLDLAKNR LYQAIQRADD ILDLKFCMDG VQTALRSEDY EQAAAHTHRY LCLDKSVIEL SRQGKEGSMI DANLKLLQEA EQRLKAIVAE KFAIATKEGD LPQVERFFKI FPLLGLHEEG LRKFSEYLCK QVASKAEENL LMVLGTDMSD RRAAVIFADT LTLLFEGIAR IVETHQPIVE TYYGPGRLYT LIKYLQVECD RQVEKVVDKF IKQRDYHQQF RHVQNNLMRN STTEKIEPRE LDPILTEVTL MNARSELYLR FLKKRISSDF EVGDSMASEE VKQEHQKCLD KLLNNCLLSC TMQELIGLYV TMEEYFMRET VNKAVALDTY EKGQLTSSMV DDVFYIVKKC IGRALSSSSI DCLCAMINLA TTELESDFRD VLCNKLRMGF PATTFQDIQR GVTSAVNIMH SSLQQGKFDT KGIESTDEAK MSFLVTLNNV EVCSENISTL KKTLESDCTK LFSQGIGGEQ AQAKFDSCLS DLAAVSNKFR DLLQEGLTEL NSTAIKPQVQ PWINSFFSVS HNIEEEEFND YEANDPWVQQ FILNLEQQMA EFKASLSPVI YDSLTGLMTS LVAVELEKVV LKSTFNRLGG LQFDKELRSL IAYLTTVTTW TIRDKFARLS QMATILNLER VTEILDYWGP NSGPLTWRLT PAEVRQVLAL RIDFRSEDIK RLRL
3D Structure
ModBase 3D Structure for Q9H9E3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of COG4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for COG4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001182068.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001195139.1
[Other Products]
UniProt Primary Accession #
Q9H9E3
[Other Products]
UniProt Secondary Accession #
Q96D40; Q9BRF0; Q9BVZ2; Q9H5Y4; Q9Y3W3; B4DMN8; C9JS23[Other Products]
UniProt Related Accession #
Q9H9E3[Other Products]
Molecular Weight
81,098 Da
NCBI Official Full Name
conserved oligomeric Golgi complex subunit 4 isoform 2
NCBI Official Synonym Full Names
component of oligomeric golgi complex 4
NCBI Official Symbol
COG4 [Similar Products]
NCBI Official Synonym Symbols
COD1; CDG2J
[Similar Products]
NCBI Protein Information
conserved oligomeric Golgi complex subunit 4
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 4
UniProt Synonym Protein Names
Component of oligomeric Golgi complex 4
Protein Family
Conserved oligomeric Golgi complex
UniProt Gene Name
COG4 [Similar Products]
UniProt Synonym Gene Names
COG complex subunit 4 [Similar Products]
NCBI Summary for COG4
The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
UniProt Comments for COG4
Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
Research Articles on COG4
1. A novel R729W missense mutation in COG4 was associated with the congenital disorder of glycosylation type II.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
