Full Product Name
AMD1 Antibody, FITC conjugated
Product Synonym Names
S-adenosylmethionine decarboxylase proenzyme; AdoMetDC; SAMDC; S-adenosylmethionine decarboxylase alpha chainS-adenosylmethionine decarboxylase beta chain; AMD1; AMD
Product Gene Name
anti-AMD1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P17707
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human S-adenosylmethionine decarboxylase proenzyme protein (167-264AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160950 / sc-98569
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AMD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AMD1 antibody
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels (By similarity).
Applications Tested/Suitable for anti-AMD1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for AMD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001625.2
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NCBI GenBank Nucleotide #
NM_001634.5
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UniProt Primary Accession #
P17707
[Other Products]
UniProt Secondary Accession #
Q5VXN4; Q5VXN6; Q9BWK4; E1P5F7[Other Products]
UniProt Related Accession #
P17707[Other Products]
Molecular Weight
21,301 Da
NCBI Official Full Name
S-adenosylmethionine decarboxylase proenzyme isoform 1
NCBI Official Synonym Full Names
adenosylmethionine decarboxylase 1
NCBI Official Symbol
AMD1 [Similar Products]
NCBI Official Synonym Symbols
AMD; SAMDC; ADOMETDC
[Similar Products]
NCBI Protein Information
S-adenosylmethionine decarboxylase proenzyme
UniProt Protein Name
S-adenosylmethionine decarboxylase proenzyme
Protein Family
S-adenosylmethionine decarboxylase proenzyme
UniProt Gene Name
AMD1 [Similar Products]
UniProt Synonym Gene Names
AMD; AdoMetDC; SAMDC [Similar Products]
UniProt Entry Name
DCAM_HUMAN
NCBI Summary for AMD1
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]
UniProt Comments for AMD1
AMD1: an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.[provided by RefSeq, Jul 2010]
Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; EC 4.1.1.50; Lyase
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: cytosol
Molecular Function: adenosylmethionine decarboxylase activity; putrescine binding
Biological Process: polyamine metabolic process; spermidine biosynthetic process; spermine biosynthetic process
Research Articles on AMD1
1. AMD1 gene variants previously found to associate among Indian children did not associate with risk of obesity or obesity-related quantitative measures among Caucasian children and juvenile men from Denmark.
Precautions
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Disclaimer
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