Full Product Name
RL35A Polyclonal Antibody
Product Synonym Names
60S ribosomal protein L35a; Cell growth-inhibiting gene 33 protein; RPL35A; GIG33
Product Gene Name
anti-RL35A antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P18077
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 1-80
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-RL35A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RL35A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-RL35A antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for RL35A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000987.2
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NCBI GenBank Nucleotide #
NM_000996.4
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UniProt Primary Accession #
P18077
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UniProt Secondary Accession #
Q08ES9; Q9BVN7[Other Products]
UniProt Related Accession #
P18077[Other Products]
NCBI Official Full Name
60S ribosomal protein L35a
NCBI Official Synonym Full Names
ribosomal protein L35a
NCBI Official Symbol
RPL35A [Similar Products]
NCBI Official Synonym Symbols
DBA5; L35A; eL33
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NCBI Protein Information
60S ribosomal protein L35a
UniProt Protein Name
60S ribosomal protein L35a
UniProt Synonym Protein Names
Cell growth-inhibiting gene 33 protein; Large ribosomal subunit protein eL33
UniProt Gene Name
RPL35A [Similar Products]
NCBI Summary for RL35A
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L35AE family of ribosomal proteins. It is located in the cytoplasm. The rat protein has been shown to bind to both initiator and elongator tRNAs, and thus, it is located at the P site, or P and A sites, of the ribosome. Although this gene was originally mapped to chromosome 18, it has been established that it is located at 3q29-qter. Alternative splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Oct 2015]
UniProt Comments for RL35A
Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
Research Articles on RL35A
1. We identified 85 overlapping deletions, of which six included the RPL35A gene and all should be had Diamond-Blackfan anemia (DBA).we sequenced the remaining RNF168 gene and examined her fibroblast culture for a DNA double strand break repair deficiency. These results were normal, indicating that the immunodeficiency is unlikely to result from a RNF168 deficiency.
Precautions
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Disclaimer
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