Product Name
C1R, cDNA Clone
Popular Item
Full Product Name
C1R cDNA Clone
Product Gene Name
C1R cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtggctct tgtacctcct ggtgccggcc ctgttctgca gggcaggagg ctccattccc atccctcaga agttatttgg ggaggtgact tcccctctgt tccccaagcc ttaccccaac aactttgaaa caaccactgt gatcacagtc cccacgggat acagggtgaa gctcgtcttc cagcagtttg acctggagcc ttctgaaggc tgcttctatg attatgtcaa gatctctgct gataagaaaa gcctggggag gttctgtggg caactgggtt ctccactggg caaccccccg ggaaagaagg aatttatgtc ccaagggaac aagatgctgc tgaccttcca cacagacttc tccaacgagg agaatgggac catcatgttc tacaagggct tcctggccta ctaccaagct gtggaccttg atgaatgtgc ttcccggagc aaattagggg aggaggatcc ccagccccag tgccagcacc tgtgtcacaa ctacgttgga ggctacttct gttcctgccg tccaggctat gagcttcagg aagacaggca ttcctgccag gctgagtgca gcagcgagct gtacacggag gcatcaggct acatctccag cctggagtac cctcggtcct acccccctga cctgcgctgc aactacagca tccgggtgga gcggggcctc accctgcacc tcaagttcct ggagcctttt gatattgatg accaccagca agtacactgc ccctatgacc agctacagat ctatgccaac gggaagaaca ttggcgagtt ctgtgggaag caaaggcccc ccgacctcga caccagcagc aatgctgtgg atctgctgtt cttcacagat gagtcggggg acagccgggg ctggaagctg cgctacacca ccgagatcat caagtgcccc cagcccaaga ccctagacga gttcaccatc atccagaacc tgcagcctca gtaccagttc cgtgactact tcattgctac ctgcaagcaa ggctaccagc tcatagaggg gaaccaggtg ctgcattcct tcacagctgt ctgccaggat gatggcacgt ggcatcgtgc catgcccaga tgcaagatca aggactgtgg gcagccccga aacctgccta atggtgactt ccgttacacc accacaatgg gagtgaacac ctacaaggcc cgtatccagt actactgcca tgagccatat tacaagatgc agaccagagc tggcagcagg gagtctgagc aaggggtgta cacctgcaca gcacagggca tttggaagaa tgaacagaag ggagagaaga ttcctcggtg cttgccagtg tgtgggaagc ccgtgaaccc cgtggaacag aggcagcgca tcatcggagg gcaaaaagcc aagatgggca acttcccctg gcaggtgttc accaacatcc acgggcgcgg gggcggggcc ctgctgggcg accgctggat cctcacagct gcccacaccc tgtatcccaa ggaacacgaa gcgcaaagca acgcctcttt ggatgtgttc ctgggccaca caaatgtgga agagctcatg aagctaggaa atcaccccat ccgcagggtc agcgtccacc cggactaccg tcaggatgag tcctacaatt ttgaggggga catcgccctg ctggagctgg aaaatagtgt caccctgggt cccaacctcc tccccatctg cctccctgac aacgatacct tctacgacct gggcttgatg ggctatgtca gtggcttcgg ggtcatggag gagaagattg ctcatgacct caggtttgtc cgtctgcccg tagctaatcc acaggcctgt gagaactggc tccggggaaa gaataggatg gatgtgttct ctcaaaacat gttctgtgct ggacacccat ctctaaagca ggacgcctgc cagggggata gtgggggcgt ttttgcagta agggacccga acactgatcg ctgggtggcc acgggcatcg tgtcctgggg catcgggtgc agcaggggct atggcttcta caccaaagtg ctcaactacg tggactggat caagaaagag atggaggagg aggactga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of C1R cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C1R. It may not necessarily be applicable to this product.
NCBI Accession #
BC035220
[Other Products]
UniProt Secondary Accession #
Q68D77; Q8J012; A6NJQ8[Other Products]
UniProt Related Accession #
P00736[Other Products]
Molecular Weight
80,119 Da
NCBI Official Full Name
Homo sapiens complement component 1, r subcomponent, mRNA
NCBI Official Synonym Full Names
complement C1r
NCBI Official Symbol
C1R [Similar Products]
NCBI Protein Information
complement C1r subcomponent
UniProt Protein Name
Complement C1r subcomponent
UniProt Synonym Protein Names
Complement component 1 subcomponent r
Protein Family
Complement C1r subcomponent
UniProt Gene Name
C1R [Similar Products]
UniProt Entry Name
C1R_HUMAN
UniProt Comments for C1R
C1R: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. Belongs to the peptidase S1 family.
Protein type: EC 3.4.21.41; Protease
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: extracellular region
Molecular Function: protein binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: complement activation; complement activation, classical pathway; immune response
Disease: Complement Component C1r/c1s Deficiency; Ehlers-danlos Syndrome, Periodontal Type, 1
Research Articles on C1R
1. C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r/C1s proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1. T
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
