inositol 1, 4, 5-trisphosphate 3-kinase C, ELISA Kit

Human Inositol-trisphosphate 3-kinase C (ITPKC) ELISA kit; IP3KC; InsP 3 kinase C; inositol 1; 4; 5-trisphosphate 3-kinase C

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of ITPKC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9330213 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the inositol 1, 4, 5-trisphosphate 3-kinase C (ITPKC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITPKC. The ELISA analytical biochemical technique of the MBS9330213 kit is based on ITPKC antibody-ITPKC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITPKC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITPKC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

75,207 Da

inositol-trisphosphate 3-kinase C

inositol-trisphosphate 3-kinase C; IP3K C; IP3 3-kinase C; InsP 3 kinase C; insP 3-kinase C; inositol 1,4,5-trisphosphate 3-kinase C

Inositol-trisphosphate 3-kinase C

IP3KC; IP3 3-kinase C; IP3K C; InsP 3-kinase C  [Similar Products]

IP3KC_HUMAN

This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.[provided by RefSeq, Sep 2009]

ITPKC: Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. Defects in ITPKC are a cause of Kawasaki disease (KWD); also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self- limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries. Belongs to the inositol phosphokinase (IPK) family.

Protein type: EC 2.7.1.127; Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: nucleus; cytosol

Molecular Function: calmodulin binding; inositol trisphosphate 3-kinase activity; ATP binding

Biological Process: inositol phosphate metabolic process; phosphorylation

Disease: Kawasaki Disease

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