Product Name
C1r LC, Polyclonal Antibody
Full Product Name
Cleaved-C1r LC (I464) Polyclonal Antibody
Product Gene Name
anti-C1r LC antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P00736
Other Notes
Small volumes of anti-C1r LC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C1r LC. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001724.3
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NCBI GenBank Nucleotide #
NM_001733.4
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UniProt Primary Accession #
P00736
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UniProt Secondary Accession #
Q68D77; Q8J012; A6NJQ8[Other Products]
UniProt Related Accession #
P00736[Other Products]
Molecular Weight
80,119 Da
NCBI Official Full Name
complement C1r subcomponent
NCBI Official Synonym Full Names
complement C1r
NCBI Official Symbol
C1R [Similar Products]
NCBI Official Synonym Symbols
EDSPD1
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NCBI Protein Information
complement C1r subcomponent
UniProt Protein Name
Complement C1r subcomponent
UniProt Synonym Protein Names
Complement component 1 subcomponent r
UniProt Gene Name
C1R [Similar Products]
UniProt Comments for C1r LC
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Research Articles on C1r LC
1. The serine protease domains of C1r and C1s are at the periphery of the C1r2s2 tetramer both when alone or within the nonactivated C1 complex. The C1 complex adopts a conformation incompatible with intramolecular activation of C1. Instead, intermolecular proteolytic activation between neighboring C1 complexes bound to a complement-activating surface occurs. Many structurally unrelated molecular patterns can activate C1.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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