Product Name
SLC6A8, Polyclonal Antibody
Full Product Name
SLC6A8 Polyclonal Antibody
Product Gene Name
anti-SLC6A8 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P48029
Other Notes
Small volumes of anti-SLC6A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC6A8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001136277.1
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NCBI GenBank Nucleotide #
NM_001142805.1
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UniProt Primary Accession #
P48029
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UniProt Secondary Accession #
Q13032; Q66I36; B2KY47; B4DIA3; E9PFC0[Other Products]
UniProt Related Accession #
P48029[Other Products]
Molecular Weight
58,453 Da
NCBI Official Full Name
sodium- and chloride-dependent creatine transporter 1 isoform 2
NCBI Official Synonym Full Names
solute carrier family 6 member 8
NCBI Official Symbol
SLC6A8 [Similar Products]
NCBI Official Synonym Symbols
CRT; CT1; CRTR; CTR5; CCDS1
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NCBI Protein Information
sodium- and chloride-dependent creatine transporter 1
UniProt Protein Name
Sodium- and chloride-dependent creatine transporter 1
UniProt Synonym Protein Names
Solute carrier family 6 member 8
Protein Family
Sodium- and chloride-dependent creatine transporter
UniProt Gene Name
SLC6A8 [Similar Products]
UniProt Synonym Gene Names
CT1; Creatine transporter 1 [Similar Products]
NCBI Summary for SLC6A8
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
UniProt Comments for SLC6A8
Required for the uptake of creatine in muscles and brain.
Research Articles on SLC6A8
1. Measurements of creatine and guanidinoacetate in plasma are recommended for the diagnosis of AGAT and GAMT deficiency.Definitive confirmation of the diagnosis requires DNA sequencing of the appropriate gene and (if molecular analysis is ambiguous) measurement of AGAT or GAMT enzyme activity or of CRTR-mediated transport
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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