Product Name
DPF3, cDNA Clone
Full Product Name
DPF3 cDNA Clone
Product Gene Name
DPF3 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcgactg tcattcacaa ccccctgaaa gcgctcgggg accagttcta caaggaagcc attgagcact gccggagtta caactcacgg ctgtgtgcag agcgcagcgt gcgtcttccc ttcctggact cacagactgg ggtggcccag aacaactgct acatctggat ggagaagagg caccgaggcc caggccttgc cccgggccag ctgtatacat accctgcccg ctgctggcgc aagaagagac gactgcaccc acctgaagat ccaaaactgc ggctgctgga gataaaacct gaagtggagc ttcccctgaa gaaggatggg ttcacctcag agagcaccac gctggaagcc ttgctccgtg gcgagggggt tgagaagaag gtggatgcca gggaggagga aagcatccag gaaatacaga gggttttgga aaatgatgaa aatgtagaag aagggaatga agaagaggat ttggaagagg atattcccaa gcgaaagaac aggactagag gacgggctca cggctctgca gggggcagga ggaggcacga cgccgcctct caggaagacc acgacaaacc ttacgtctgt gacatctgtg gcaagcgcta caagaaccga ccggggctca gctaccacta tgctcacact cacctggcca gcgaggaggg ggatgaagct caagaccagg agactcggtc cccacccaac cacagaaatg agaaccacag gccccagaaa ggaccggatg gaacagtcat tcccaataac tactgtgact tctgcttggg gggctccaac atgaacaaga agagtgggcg gcctgaagag ctggtgtcct gcgcagactg tggacgctct gctcatttgg gaggagaagg caggaaggag aaggaggcag cggccgcagc acgtaccacg gaggacttat tcggttccac gtcagaaagt gacacgtcaa ctttccgcgg ctttgatgag gacgatttgg aagagcctcg ctcctgtcga ggacgccgca gtggccgggg ttcgcccaca gcagataaaa agggcagttg ctaa
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of DPF3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DPF3. It may not necessarily be applicable to this product.
NCBI Accession #
BC060801
[Other Products]
UniProt Secondary Accession #
Q32UJ0; Q6P9E6; Q6ZT41; Q9H7Y5; A8MSI3; B7Z276; F5H575[Other Products]
UniProt Related Accession #
Q92784[Other Products]
Molecular Weight
41,184 Da
NCBI Official Full Name
Homo sapiens D4, zinc and double PHD fingers, family 3, mRNA
NCBI Official Synonym Full Names
double PHD fingers 3
NCBI Official Symbol
DPF3 [Similar Products]
NCBI Official Synonym Symbols
CERD4; BAF45C
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NCBI Protein Information
zinc finger protein DPF3
UniProt Protein Name
Zinc finger protein DPF3
UniProt Synonym Protein Names
BRG1-associated factor 45C; BAF45C; Zinc finger protein cer-d4
Protein Family
Zinc finger protein
UniProt Gene Name
DPF3 [Similar Products]
UniProt Synonym Gene Names
BAF45C; CERD4; BAF45C [Similar Products]
UniProt Entry Name
DPF3_HUMAN
NCBI Summary for DPF3
This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
UniProt Comments for DPF3
DPF3: Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their ***** state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development. Belongs to the requiem/DPF family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 14q24.2
Biological Process: positive regulation of defense response to virus by host
Research Articles on DPF3
1. Immunohistochemical staining showed that intensive DPF3 staining occurred in proximal anastomosis and the positive staining was hardly observed in stenotic segment in colon specimens from patients with Hirschsprung's disease
Precautions
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Disclaimer
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