Product Name
ADCY5, Blocking Peptide
Full Product Name
ADCY5 Peptide
Product Synonym Names
AC 5; Adcy5; Adenylate cyclase type V; Adenylyl cyclase 5; ATP pyrophosphate-lyase 5 antibody
Product Gene Name
ADCY5 blocking peptide
[Similar Products]
ADCY5 peptide (MBS544103) is used for blocking the activity of ADCY5 antibody (MBS542318)
Antibody/Peptide Pairs
ADCY5 peptide (MBS544103) is used for blocking the activity of ADCY5 antibody (MBS542319)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q04400
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (lot specific)
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein.
Molecular Function
Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding
Structure
Part of a complex containing AKAP5, ADCY6, PDE4C and PKD2. Interacts with RAF1.
Subcellular Location
Membrane; Multi-pass membrane protein; Cell projection; cilium
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of ADCY5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ADCY5 blocking peptide
Antigenic Blocking Peptide Adenylyl cyclase type 5
Membrane bound calcium-inhibitable adenylyl cyclase.
Applications Tested/Suitable for ADCY5 blocking peptide
Immunodepletion, Immunocompetition
Application Notes for ADCY5 blocking peptide
Confocal Microscopy||1:200-1:1,000
Immunocytochemistry: 1:200-1:1,000
Immunofluorescence: 1:200-1:1,000
Immunohistochemistry: 1:200-1:1,000
Western Blot: 1:500
NCBI/Uniprot data below describe general gene information for ADCY5. It may not necessarily be applicable to this product.
NCBI Accession #
M96159.1
[Other Products]
UniProt Primary Accession #
Q04400
[Other Products]
UniProt Related Accession #
Q04400[Other Products]
Molecular Weight
139,179 Da
NCBI Official Full Name
Rattus norvegicus adenylyl cyclase type V mRNA, complete cds
NCBI Official Synonym Full Names
adenylate cyclase 5
NCBI Official Symbol
Adcy5 [Similar Products]
NCBI Protein Information
adenylate cyclase type 5
UniProt Protein Name
Adenylate cyclase type 5
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5
Protein Family
Adenylate cyclase
UniProt Gene Name
Adcy5 [Similar Products]
UniProt Entry Name
ADCY5_RAT
NCBI Summary for ADCY5
enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate [RGD, Feb 2006]
UniProt Comments for ADCY5
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:1409703). Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion.
Research Articles on ADCY5
1. Increased expression of adenylyl cyclases V and VI is a major determinant of increased GABAergic transmission in the substantia nigra pars reticulata of animals in which L-DOPA induces severe dyskinesia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
