Product Name
TBX15, cDNA Clone
Full Product Name
TBX15 cDNA Clone
Product Gene Name
TBX15 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGTCTTCCA TGGAGGAGAT TCAGGTGGAG CTGCAATGTG CTGACCTCTG GAAGCGGTTC CATGATATTG GAACTGAAAT GATCATCACC AAAGCAGGCA GGAGGATGTT TCCTGCCATG AGAGTGAAAA TCACTGGCCT AGATCCACAT CAGCAGTACT ACATAGCAAT GGACATTGTG CCTGTGGACA ATAAAAGATA CAGATATGTG TATCATAGCT CCAAGTGGAT GGTGGCTGGC AATGCTGATT CCCCTGTGCC CCCAAGAGTT TATATACACC CTGATTCTCT AGCTTCTGGA GACACCTGGA TGAGACAGGT GGTCAGTTTT GACAAACTCA AGCTTACCAA CAATGAGTTG GATGATCAAG GACATATCAT TCTGCACTCT ATGCACAAAT ACCAGCCTCG AGTTCATGTG ATTCGCAAAG ACTTCAGCAG TGACCTTTCA CCCACTAAGC CTGTTCCTGT TGGGGATGGG GTGAAAACGT TCAACTTTCC TGAGACTGTG TTCACCACAG TTACGGCCTA TCAGAATCAG CAGATTACCA GATTAAAAAT TGACCGAAAC CCTTTTGCTA AAGGATTCAG AGATTCTGGG AGAAACAGAA CTGGACTTGA AGCCATCATG GAGACATATG CATTCTGGAG ACCTCCTGTG CGCACACTCA CCTTCGAAGA CTTCACCACC ATGCAGAAGC AGCAAGGAGG CAGCACAGGC ACTTCCCCAA CCACCTCCAG CACTGGGACA CCATCCCCTT CGGCTTCTTC TCATCTTTTA TCTCCATCCT GTTCTCCTCC AACTTTTCAT CTGGCCCCCA ACACTTTCAA TGTGGGCTGC CGAGAAAGCC AGCTGTGTAA TCTAAACCTC TCTGATTATC CACCATGTGC CCGAAGCAAC ATGGCTGCCT TGCAGAGCTA CCCAGGGCTG AGTGACAGTG GCTACAACAG GCTTCAGAGT GGCACCACTT CAGCCACTCA GCCCTCTGAA ACCTTCATGC CTCAGAGGAC TCCATCCCTG ATCTCAGGAA TACCAACTCC TCCCTCGTTG CCTGGCAACA GCAAGATGGA AGCCTACGGT GGCCAGCTGG GGTCCTTTCC CACTTCCCAG TTTCAGTATG TCATGCAGGC AGGCAATGCT GCCTCCAGCT CCTCATCACC ACACATGTTC GGGGGCAGCC ACATGCAGCA GAGCTCCTAC AATGCCTTCT CCCTTCACAA CCCTTACAAC CTGTATGGAT ACAATTTCCC CACTTCCCCT AGGCTAGCTG CAAGCCCGGA AAAACTGAGC GCCTCTCAAA GCACTTTACT CTGTTCTTCT CCTTCCAACG GGGCCTTTGG AGAGAGGCAG TACCTGCCGT CAGGGATGGA GCACAGCATG CACATGATTA GTCCTTCACC CAATAACCAA CAGGCAACCA ACACTTGTGA TGGCCGGCAG TATGGGGCAG TTCCAGGCTC CTCCTCCCAG ATGTCCGTGC ACATGGTTTA A
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TBX15 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TBX15. It may not necessarily be applicable to this product.
NCBI Accession #
BC122553
[Other Products]
UniProt Secondary Accession #
Q08E76; Q5JT54; Q5T9S7[Other Products]
UniProt Related Accession #
Q96SF7[Other Products]
Molecular Weight
54,671 Da
NCBI Official Full Name
Homo sapiens T-box 15, mRNA
NCBI Official Synonym Full Names
T-box 15
NCBI Official Symbol
TBX15 [Similar Products]
NCBI Official Synonym Symbols
TBX14
[Similar Products]
NCBI Protein Information
T-box transcription factor TBX15
UniProt Protein Name
T-box transcription factor TBX15
UniProt Synonym Protein Names
T-box transcription factor TBX14; T-box protein 14
Protein Family
T-box transcription factor
UniProt Gene Name
TBX15 [Similar Products]
UniProt Synonym Gene Names
TBX14; T-box protein 15; T-box protein 14 [Similar Products]
UniProt Entry Name
TBX15_HUMAN
NCBI Summary for TBX15
This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
UniProt Comments for TBX15
TBX15: Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes. Defects in TBX15 are the cause of Cousin syndrome (COUSS); also known as craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature. Cousin syndrome is defined as pelviscapular dysplasia with epiphyseal abnormalities, congenital dwarfism and facial dysmorphy (frontal bossing, hypertelorism, narrow palpebral fissures, deep set globes, strabismus, low-set posteriory rotated and unusually formed external ears, dysplasia of conchae, small chin, short neck with redundant skin folds, and a low hairline). Intelligence may vary from normal to moderately impaired. Radiographic features comprise aplasia of the body of the scapula, hypoplasia of the iliac bone, humeroradial synosthosis, dislocation of the femoral heads, and moderate brachydactyly. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p11.1
Molecular Function: protein binding
Disease: Cousin Syndrome
Research Articles on TBX15
1. The results indicate the antiapoptotic role of TBX15 in cancer cells, suggesting a contribution of TBX15 in carcinogenesis.
Precautions
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Disclaimer
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