Product Name
GABRA6, Polyclonal Antibody
Full Product Name
GABRA6 antibody
Product Synonym Names
Rabbit polyclonal GABRA6 antibody; Polyclonal GABRA6 antibody; Anti-GABRA6 antibody; GABRA 6 antibody; GABRA-6 antibody; GABRA6; Gamma aminobutyric acid (GABA) A receptor alpha 6 antibody
Product Gene Name
anti-GABRA6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16445
Other Notes
Small volumes of anti-GABRA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GABRA6 antibody
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Product Categories/Family for anti-GABRA6 antibody
Neuroscience
Applications Tested/Suitable for anti-GABRA6 antibody
Western Blot (WB)
Application Notes for anti-GABRA6 antibody
WB: 1:1000
Testing Data of anti-GABRA6 antibody
Western blot of rat cortex lysate showing immunolabeling of ~57k alpha6-subunit of the GABAA receptor
NCBI/Uniprot data below describe general gene information for GABRA6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000802.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000811.2
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UniProt Primary Accession #
Q16445
[Other Products]
UniProt Secondary Accession #
Q4VAV2; A8K096[Other Products]
UniProt Related Accession #
Q16445[Other Products]
Molecular Weight
51,024 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit alpha-6
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor alpha6 subunit
NCBI Official Symbol
GABRA6 [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-6
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-6
UniProt Synonym Protein Names
GABA(A) receptor subunit alpha-6
Protein Family
Gamma-aminobutyric acid receptor
UniProt Gene Name
GABRA6 [Similar Products]
NCBI Summary for GABRA6
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRA6
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Research Articles on GABRA6
1. TMEM132D, COMT and GABRA6 gene polymorphisms may influence susceptibility to panic disorder(PD) and major depressive disorder(MDD)in Japanese *****s; these variants may increase vulnerability to PD by modulating oligodendrocytes and GABA and dopaminergic functions in related brain regions, altering neuronal processing of anxiety-related emotional signals
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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