Product Name
Phosphate carrier protein (Slc25a3), Recombinant Protein
Full Product Name
Recombinant Mouse Phosphate carrier protein, mitochondrial (Slc25a3)
Product Gene Name
Slc25a3 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
46-357aa; full length protein
Sequence
AVEEYSCEFG SMKYYALCGF GGVLSCGLTH TAVVPLDLVK CRMQVDPQKY KGIFNGFSIT LKEDGVRGLA KGWAPTLIGY SMQGLCKFGF YEVFKALYSN ILGEENTYLW RTSLYLASSA SAEFFADIAL APMEAAKVRI QTQPGYANTL REAVPKMYKE EGLNAFYKGV APLWMRQIPY TMMKFACFER TVEALYKFVV PKPRSECTKA EQLVVTFVAG YIAGVFCAIV SHPADSVVSV LNKEKGSTAS QVLQRLGFRG VWKGLFARII MIGTLTALQW FIYDSVKVYF RLPRPPPPEM PESLKKKLGL TE
3D Structure
ModBase 3D Structure for Q8VEM8
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Slc25a3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Slc25a3 recombinant protein
Transmembrane Protein
Application Notes for Slc25a3 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Slc25a3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_598429.1
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NCBI GenBank Nucleotide #
NM_133668.3
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UniProt Primary Accession #
Q8VEM8
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UniProt Secondary Accession #
Q542V7[Other Products]
UniProt Related Accession #
Q8VEM8[Other Products]
Molecular Weight
39,632 Da
NCBI Official Full Name
phosphate carrier protein, mitochondrial
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
NCBI Official Symbol
Slc25a3 [Similar Products]
NCBI Official Synonym Symbols
PTP; Phc; 5730556H19Rik
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NCBI Protein Information
phosphate carrier protein, mitochondrial
UniProt Protein Name
Phosphate carrier protein, mitochondrial
UniProt Synonym Protein Names
Phosphate transport protein; PTP; Solute carrier family 25 member 3
UniProt Gene Name
Slc25a3 [Similar Products]
UniProt Synonym Gene Names
PTP [Similar Products]
UniProt Entry Name
MPCP_MOUSE
UniProt Comments for Slc25a3
SLC25A3: Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD). MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life. Belongs to the mitochondrial carrier family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, SLC family; Transporter; Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: integral to membrane; membrane; mitochondrial inner membrane; mitochondrion; myelin sheath; nucleolus; nucleus
Molecular Function: protein complex binding; structural constituent of ribosome; symporter activity
Biological Process: translation; transport
Research Articles on Slc25a3
1. The mitochondrial PiC is not a critical component of the MPT pore.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
