Full Product Name
Anti-human CD32 Antibody Unconjugated, Flow Validated
Product Synonym Names
Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32; FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Product Gene Name
anti-CD32 antibody
[Similar Products]
Product Synonym Gene Name
FCGR2A[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P12318
Purity/Purification
Protein A purified
Immunogen
K-562 human erythromyeloblastoid leukemia cell line
Subcellular Localization
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Found on monocytes, neutrophils and eosinophil platelets.
Sensitivity
5ul per sample
Contents
PBS, pH7.2, 0.09% NaN3
Preparation and Storage
Store at 4 degree C. Do not freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CD32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD32 antibody
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Product Categories/Family for anti-CD32 antibody
Immunology; immunoGlobulins; Receptors; Stem Cells; Hematopoietic Progenitors; Lymphoid; B Lymphocytic Lineage; T Lymphocytic Lineage; Myeloid; monocytic lineage; mast cell lineage
Applications Tested/Suitable for anti-CD32 antibody
Flow Cytometry (FC/FACS)
Testing Data of anti-CD32 antibody
Monocytes gated PBMCs stained withpurified anti-human CD32 (clone IV.3)followed by Goat anti-mouse IgG (H+L)Alexa Fluor 488 (red histogram).Monocytes gated PBMCs stained withonly Goat anti-mouse IgG (H+L) AlexaFluor 488 (Blue histogram).
NCBI/Uniprot data below describe general gene information for CD32. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129691.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001136219.1
[Other Products]
UniProt Primary Accession #
P12318
[Other Products]
UniProt Secondary Accession #
Q8WUN1; Q8WW64[Other Products]
UniProt Related Accession #
P12318[Other Products]
Molecular Weight
35001 MW
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-a isoform 1
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIa
NCBI Official Symbol
FCGR2A [Similar Products]
NCBI Official Synonym Symbols
CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
[Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD_antigen: CD32
Protein Family
CD320 antigen
UniProt Gene Name
FCGR2A [Similar Products]
UniProt Synonym Gene Names
CD32; FCG2; FCGR2A1; IGFR2; IgG Fc receptor II-a; Fc-gamma-RIIa; FcRII-a [Similar Products]
NCBI Summary for CD32
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
UniProt Comments for CD32
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Research Articles on CD32
1. FCGR2A rs1801274 G-allele confers susceptibility to Kawasaki disease and Ulcerative colitis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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