ENTPD6, Polyclonal Antibody

CD39L2; DKFZp781G2277; DKFZp781K21102; FLJ36711; IL-6SAG; IL6ST2; NTPDase-6; dJ738P15.3

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Antigen affinity purification

Store at -20 degree C. Avoid freeze / thaw cycles

Manufactured in an ISO 9001:2015 Certified Laboratory.

Small volumes of anti-ENTPD6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

WB: 1:200-1:2000
IHC: 1:50-1:200

53,118 Da

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

ectonucleoside triphosphate diphosphohydrolase 6; CD39 antigen-like 2; CD39-like 2; HCV-E2 binding protein 1; NTPDase 6; ectonucleoside triphosphate diphosphohydrolase 6 (putative function); interleukin 6 signal transducer-2

Ectonucleoside triphosphate diphosphohydrolase 6

CD39L2; IL6ST2; NTPDase 6  [Similar Products]

ENTP6_HUMAN

ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, integral; Hydrolase; EC 3.6.1.6

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: Golgi membrane; extracellular space; cell surface; integral to membrane; plasma membrane

Molecular Function: nucleoside-triphosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; uridine-diphosphatase activity

Biological Process: response to magnesium ion; metabolic process; response to calcium ion

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