Full Product Name
Anti-CD32 Rabbit pAb
Product Gene Name
anti-CD32 antibody
[Similar Products]
Product Synonym Gene Name
CD32; CD32A; CD32B; CD32C; FCG2; FcGR; FCGR2; FCGR2A; FCGR2B; FCGR2C; Fcgr3a; FCRII; IGFR2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P12318
Specificity
CD32 Antibody detects endogenous levels of total CD32
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human CD32
Subcellular Location
Cell membrane; Single-pass type I membrane protein
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Other Notes
Small volumes of anti-CD32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD32 antibody
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens.
Applications Tested/Suitable for anti-CD32 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CD32 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
Western Blot (WB) of anti-CD32 antibody
Western blot analysis of CD32 expression in K562 cell lysate.
NCBI/Uniprot data below describe general gene information for CD32. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129691.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001136219.1
[Other Products]
UniProt Primary Accession #
P12318
[Other Products]
UniProt Secondary Accession #
Q8WUN1; Q8WW64[Other Products]
UniProt Related Accession #
P12318[Other Products]
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-a isoform 1
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIa
NCBI Official Symbol
FCGR2A [Similar Products]
NCBI Official Synonym Symbols
CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
[Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD_antigen: CD32
Protein Family
CD320 antigen
UniProt Gene Name
FCGR2A [Similar Products]
UniProt Synonym Gene Names
CD32; FCG2; FCGR2A1; IGFR2; IgG Fc receptor II-a; Fc-gamma-RIIa; FcRII-a [Similar Products]
NCBI Summary for CD32
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
UniProt Comments for CD32
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Research Articles on CD32
1. When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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