Product Name
Ghrelin O-acyltransferase (Mboat4), Recombinant Protein
Full Product Name
Recombinant Mouse Ghrelin O-acyltransferase (Mboat4)
Product Synonym Names
Recombinant Ghrelin O-acyltransferase (Mboat4); Ghrelin O-acyltransferase EC= 2.3.1.-; Membrane-bound O-acyltransferase domain-containing protein 4; O-acyltransferase domain-containing protein 4
Product Gene Name
Mboat4 recombinant protein
[Similar Products]
Product Synonym Gene Name
Mboat4; Gm171, Goat[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MDWLQLFFLH PLSFYQGAAF PFALLFNYLC ILDTFSTRAR YLFLLAGGGV LAFAAMGPYS LLIFIPALCA VALVSFLSPQ EVHRLTFFFQ MGWQTLCHLG LHYTEYYLGE PPPVRFYITL SSLMLLTQRV TSLSLDICEG KVEAPRRGIR SKSSFSEHLW DALPHFSYLL FFPALLGGSL CSFRRFQACV QRSSSLYPSI SFRALTWRGL QILGLECLKV ALRSAVSAGA GLDDCQRLEC IYLMWSTAWL FKLTYYSHWI LDDSLLHAAG FGAEAGQGPG EEGYVPDVDI WTLETTHRIS LFARQWNRST ALWLRRLVFR KSRRWPLLQT FAFSAWWHGL HPGQVFGFLC WSVMVKADYL IHTFANVCIR SWPLRLLYRA LTWAHTQLII AYIMLAVEGR SLSSLCQLCC SYNSLFPVMY GLLLFLLAER KDKRN
Chromosome Location
Chromosome: 8; NC_000074.6 (34115030..34125185). Location: 8 A4; 8
3D Structure
ModBase 3D Structure for P0C7A3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Mboat4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Mboat4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001119786.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001126314.2
[Other Products]
UniProt Primary Accession #
P0C7A3
[Other Products]
UniProt Secondary Accession #
B1Q004; B2RWL6[Other Products]
UniProt Related Accession #
P0C7A3[Other Products]
Molecular Weight
49,879 Da[Similar Products]
NCBI Official Full Name
ghrelin O-acyltransferase
NCBI Official Synonym Full Names
membrane bound O-acyltransferase domain containing 4
NCBI Official Symbol
Mboat4 [Similar Products]
NCBI Official Synonym Symbols
GOAT; Gm171
[Similar Products]
NCBI Protein Information
ghrelin O-acyltransferase; O-acyltransferase domain-containing protein 4; membrane-bound O-acyltransferase domain-containing protein 4
UniProt Protein Name
Ghrelin O-acyltransferase
UniProt Synonym Protein Names
Membrane-bound O-acyltransferase domain-containing protein 4
Protein Family
Ghrelin O-acyltransferase
UniProt Gene Name
Mboat4 [Similar Products]
UniProt Synonym Gene Names
Gm171; Goat; O-acyltransferase domain-containing protein 4 [Similar Products]
UniProt Entry Name
MBOA4_MOUSE
UniProt Comments for Mboat4
MBOAT4: Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. Belongs to the membrane-bound acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.3.1.-
Cellular Component: membrane; endoplasmic reticulum; integral to membrane; integral to endoplasmic reticulum membrane
Molecular Function: keto acid formate lyase activity; glucosaminyl-phosphotidylinositol O-acyltransferase activity; S-malonyltransferase activity; 3-hydroxybutyryl-CoA thiolase activity; S-acetyltransferase activity; O-octanoyltransferase activity; O-sinapoyltransferase activity; acyl-CoA N-acyltransferase activity; peptidyl-lysine N6-myristoyltransferase activity; palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity; peptidyl-lysine N6-palmitoyltransferase activity; azetidine-2-carboxylic acid acetyltransferase activity; dihydrolipoamide branched chain acyltransferase activity; succinyltransferase activity; Ras palmitoyltransferase activity; palmitoyltransferase activity; C-acyltransferase activity; C-palmitoyltransferase activity; dihydrolipoamide S-acyltransferase activity; protein-cysteine S-acyltransferase activity; N-acetyltransferase activity; serine O-acyltransferase activity; malonyltransferase activity; octanoyltransferase activity; O-succinyltransferase activity; O-palmitoyltransferase activity; sterol O-acyltransferase activity; 3-ketopimelyl-CoA thiolase activity; carnitine O-acyltransferase activity; S-succinyltransferase activity; N-acyltransferase activity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity; N-palmitoyltransferase activity; O-acyltransferase activity; acylglycerol O-acyltransferase activity; O-acetyltransferase activity; transferase activity; benzoyl acetate-CoA thiolase activity; sinapoyltransferase activity; protein-cysteine S-myristoyltransferase activity; S-acyltransferase activity; myristoyltransferase activity; N-succinyltransferase activity; acetyltransferase activity; transferase activity, transferring acyl groups; L-2-aminoadipate N-acetyltransferase activity
Biological Process: peptidyl-serine octanoylation
Research Articles on Mboat4
1. The endogenous GOAT-ghrelin-growth hormone secretagogue receptor system is not essential for the maintenance of euglycemia during prolonged calorie restriction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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